Transcriptional regulation is essential for the correct functioning of cells during development
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …

In the developing and mature brain, mitochondria act as central hubs for distinct but
interwined pathways, necessary for neural development, survival, activity, connectivity and …

The human cortex comprises diverse cell types that emerge from an initially uniform
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …

The differential cellular expression of class III β‐tubulin isotype (βIII) is reviewed in the
context of human embryological development and neoplasia. As compared to somatic …

The intensity of research on pancreatic development has increased markedly in the past 5
years, primarily for two reasons: we now know that the insulin‐producing β‐cells normally …

The expression of the cytoskeletal protein class III β-tubulin isotype is reviewed in the
context of human central nervous system development and neoplasia. Compared to …

Microtubule proteins form a dynamic component of the cytoskeleton, and play key roles in
cellular processes, such as vesicular transport, cell motility and mitosis. Expression of …

Alzheimer's disease (AD) is the most common cause of dementia worldwide with no curative
therapies currently available. Previously, global transcriptome analysis of AD brains by …

Preserving mitochondrial mass, bioenergetic functions and ROS (reactive oxygen species)
homoeostasis is key to neuronal differentiation and survival, as mitochondria produce most …

During neural development, epigenetic modulation of chromatin acetylation is part of a
dynamic, sequential and critical process to steer the fate of multipotent neural progenitors …