Molecular mechanisms of anticancer effect of rutin

A Imani, N Maleki, S Bohlouli… - Phytotherapy …, 2021 - Wiley Online Library
Because of the extensive biological functions of natural substances such as bioflavonoids,
and their high safety and low costs, they could have high priority application in the health …

Elderberry diet ameliorates motor function and prevents oxidative stress-induced cell death in rat models of Huntington disease

MH Moghaddam, AH Bayat, N Eskandari… - Brain Research, 2021 - Elsevier
Huntington's disease (HD) is an inherited neurodegenerative disorder which begins in the
striatum and then spreads to other neural areas. Known as a progressive movement …

DNA damage caused by chemotherapy has duality, and traditional Chinese medicine may be a better choice to reduce its toxicity

B Bai, Y Ma, D Liu, Y Zhang, W Zhang, R Shi… - Frontiers in …, 2024 - frontiersin.org
Background DNA damage induced by chemotherapy has duality. It affects the efficacy of
chemotherapy and constrains its application. An increasing number of studies have shown …

Natural products for the treatment of chemotherapy-related cognitive impairment and prospects of nose-to-brain drug delivery

YQ He, CC Zhou, SG Jiang, WQ Lan, F Zhang… - Frontiers in …, 2024 - frontiersin.org
Chemotherapy-related cognitive deficits (CRCI) as one of the common adverse drug
reactions during chemotherapy that manifest as memory, attention, and executive function …

Moderately intense physical exercise alleviates electrocardiographic changes induced by cisplatin in rats

MS Silva, CHL Rocha, AA Dos Santos… - Revista Portuguesa de …, 2024 - Elsevier
Introduction and objective Cisplatin induces many collateral effects such as gastrointestinal
disorders, nephrotoxicity, and dysautonomia. Recently our group showed that cisplatin …

[HTML][HTML] Protective effect of rutin trihydrate against dose-dependent, cisplatin-induced cardiac toxicity in isolated perfused rat's heart

IA Bukhari, OY Mohamed, AM Alhowikan, R Lateef… - Cureus, 2022 - ncbi.nlm.nih.gov
Background Cisplatin is a common anticancer drug with potential cardiac and renal
toxicities. Rutin, a natural compound present in various medicinal plants, has been shown to …

Exercise and pyridostigmine prevents gastric emptying delay and increase blood pressure and cisplatin-induced baroreflex sensitivity in rats

MS Silva, Y de Andrade Gomes… - Life Sciences, 2021 - Elsevier
Cisplatin treatment induces an autonomic dysfunction and gastrointestinal and
cardiovascular disorders. Physical exercise as well as pyridostigmine treatment induces …

The effect of taxifolin on oxidative sciatic nerve damage induced by cobalt chloride in rats: a biochemical and histopathological evaluation

C Tanoğlu, A Ersoy, T Çoban, R Mammadov… - Acta neurobiologiae …, 2022 - ane.pl
Cobalt is a trace element that increases lipid peroxidation and malondialdehyde levels and
reduces the antioxidant defense mechanisms of nerve cells. High levels of cobalt exposure …

[PDF][PDF] Neuroprotective Effects of Ellagic Acid, Rutin and p-Coumaric Acid on Diabetic Neuropathy Rats.

Z Fazlin, T Myo, DM Fauzi, M Resni… - Asian Journal of …, 2022 - ajmhsrcmp.org
Background: The peripheral nervous system has regenerative capability which mainly
dependent on Schwann cells plasticity. The administration of phenolic compounds may …

[PDF][PDF] 芦丁对丙烯酰胺致大鼠坐骨神经髓鞘损伤的保护作用

白艳娴, 贾会, 张桐, 罗宇悠, 张春梅, 罗利, 马宇昕… - 解剖学报, 2022 - jpxb.bjmu.edu.cn
目的通过观察芦丁(Rut) 对丙烯酰胺(ACR) 染毒大鼠坐骨神经髓鞘结构, 髓鞘碱性蛋白(MBP)
及髓鞘相关糖蛋白(MAG) 表达的变化, 探讨Rut 对ACR 致大鼠坐骨神经髓鞘损伤的保护作用 …