2024 ESC Guidelines for the management of elevated blood pressure and hypertension: Developed by the task force on the management of elevated blood pressure …

JW McEvoy, CP McCarthy, RM Bruno… - European heart …, 2024 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Evaluation and management of hypertensive emergency

JB Miller, D Hrabec, V Krishnamoorthy, H Kinni… - bmj, 2024 - bmj.com
Hypertensive emergencies cause substantial morbidity and mortality, particularly when
acute organ injury is present. Careful and effective strategies to reduce blood pressure and …

Mechanical thrombectomy for acute ischemic stroke: current state and future directions

AM Mehta, SM Desai, AP Jadhav - Current Treatment Options in …, 2024 - Springer
Purpose of review This review summarizes significant advancements in mechanical
thrombectomy (MT) to treat acute ischemic stroke after the pivotal DAWN (Clinical Mismatch …

An introduction to Bayesian approaches to trial design and statistics for stroke researchers

JM Ospel, S Brown, JK Holodinsky, L Rinkel, A Ganesh… - Stroke, 2024 - ahajournals.org
While the majority of stroke researchers use frequentist statistics to analyze and present their
data, Bayesian statistics are becoming more and more prevalent in stroke research. As …

[HTML][HTML] Individualized autoregulation-guided arterial blood pressure management in neurocritical care

JR Gomez, BU Bhende, R Mathur, LF Gonzalez… - …, 2025 - Elsevier
Cerebral autoregulation (CA) is the physiological process by which cerebral blood flow is
maintained during fluctuations in arterial blood pressure (ABP). There are various validated …

Blood pressure variability in acute stroke: a narrative review

C Zompola, L Palaiodimou, K Voumvourakis… - Journal of Clinical …, 2024 - mdpi.com
The management of blood pressure variability (BPV) in acute stroke presents a complex
challenge with profound implications for patient outcomes. This narrative review examines …

Subgroup analyses and heterogeneity of treatment effects in randomized trials: a primer for the clinician

AB Spicer, AB Cavalcanti… - Current Opinion in Critical …, 2024 - journals.lww.com
There is an increasing interest in approaches that can identify heterogeneity in treatment
effects from randomized clinical trials, extending beyond traditional subgroup analyses …

Intensive Versus Standard blood pressure management after endovascular therapy for Acute ischemic stroke: a systematic review and Meta-analysis

K Zhang, X Wang, Y Wu, F Liang, X Hou… - Journal of …, 2025 - journals.lww.com
Prospective clinical studies on blood pressure (BP) management targets after endovascular
therapy (EVT) for acute ischemic stroke (AIS) have recently been published. Our objective …

Ischemic Stroke and Reduced Left Ventricular Ejection Fraction: A Multidisciplinary Approach to Optimize Brain and Cardiac Health

KF McNamara, AE Merkler, JV Freeman, HM Krumholz… - Stroke, 2024 - Am Heart Assoc
Reduced left ventricular ejection fraction≤ 40%, a known risk factor for adverse cardiac
outcomes and recurrent acute ischemic stroke, may be detected during an acute ischemic …

Intensive vs Conventional Blood Pressure Control After Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

S Ghozy, A Mortezaei, M Elfil, M Abdelghaffar… - JAMA Network …, 2024 - jamanetwork.com
Importance Endovascular thrombectomy (EVT) is standard treatment for acute ischemic
stroke (AIS) due to large-vessel occlusion (LVO), but optimal post-EVT blood pressure (BP) …