Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …
discovery of several promising drug targets and novel therapeutic strategies to address the …
[HTML][HTML] Doxorubicin induced heart failure: Phenotype and molecular mechanisms
MA Mitry, JG Edwards - IJC heart & vasculature, 2016 - Elsevier
Long term survival of childhood cancers is now more than 70%. Anthracyclines, including
doxorubicin, are some of the most efficacious anticancer drugs available. However, its use …
doxorubicin, are some of the most efficacious anticancer drugs available. However, its use …
Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …
has been one of the most significant biochemical and pharmacological advancements to …
Cannabis: a toxin-producing plant with potential therapeutic uses
For thousands of years, Cannabis sativa has been utilized as a medicine and for
recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are …
recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are …
The impact of marijuana on the cardiovascular system: a review of the most common cardiovascular events associated with marijuana use
Z Latif, N Garg - Journal of clinical medicine, 2020 - mdpi.com
With the expanded legalization of marijuana, its medical and recreational use have sharply
increased over the past decade. A wide array of new forms of cannabis is available on the …
increased over the past decade. A wide array of new forms of cannabis is available on the …
Cardiovascular complications of marijuana and related substances: a review
The recreational use of cannabis has sharply increased in recent years in parallel with its
legalization and decriminalization in several countries. Commonly, the traditional cannabis …
legalization and decriminalization in several countries. Commonly, the traditional cannabis …
[HTML][HTML] The therapeutic potential of second and third generation CB1R antagonists
Endocannabinoids acting via CB 1 receptors (CB 1 R) play a critical role in regulating
energy homeostasis, which was the rationale for the pharmaceutical development of CB 1 R …
energy homeostasis, which was the rationale for the pharmaceutical development of CB 1 R …
New insights in cannabinoid receptor structure and signaling
L Ye, Z Cao, W Wang, N Zhou - Current molecular …, 2019 - ingentaconnect.com
Background: Cannabinoid has long been used for medicinal purposes. Cannabinoid
signaling has been considered the therapeutic target for treating pain, addiction, obesity …
signaling has been considered the therapeutic target for treating pain, addiction, obesity …
Evidence for novel cannabinoid receptors
Cannabinoids, including the bioactive constituents of the marijuana plant, their synthetic
analogs, and endogenous lipids with cannabinoid-like activity, produce their biological …
analogs, and endogenous lipids with cannabinoid-like activity, produce their biological …