Specialized pro-resolving mediators in respiratory diseases

RE Cagnina, MG Duvall, J Nijmeh… - Current Opinion in …, 2022 - journals.lww.com
Dietary marine oils are enriched in PUFAs and contain parent omega-3 and omega-6 fatty
acids and precursors for conversion to SPMs. Nutritional supplementation with fish oils can …

Air pollution and diet: potential interacting exposures in asthma

E Brigham, A Hashimoto, NE Alexis - Current Allergy and Asthma Reports, 2023 - Springer
Abstract Purpose of Review To provide a review of emerging literature describing the impact
of diet on the respiratory response to air pollution in asthma. Recent Findings Asthma …

Investigating associations of omega-3 fatty acids, lung function decline, and airway obstruction

BK Patchen, P Balte, TM Bartz, RG Barr… - American journal of …, 2023 - atsjournals.org
Rationale: Inflammation contributes to lung function decline and the development of chronic
obstructive pulmonary disease. Omega-3 fatty acids have antiinflammatory properties and …

Sex-Specific Differences in Resolution of Airway Inflammation in Fat-1 Transgenic Mice Following Repetitive Agricultural Dust Exposure

A Ulu, JV Velazquez, A Burr, SN Sveiven… - Frontiers in …, 2022 - frontiersin.org
In agriculture industries, workers are at increased risk for developing pulmonary diseases
due to inhalation of agricultural dusts, particularly when working in enclosed confinement …

Aspirin-triggered resolvin D1 modulates pulmonary and neurological inflammation in an IL-22 knock-out organic dust exposure mouse model

AN Threatt, J White, N Klepper, Z Brier… - Frontiers in …, 2024 - frontiersin.org
Agriculture dust contains many organic immunogenic compounds, and organic dust
exposure is strongly associated with the development of immune-mediated chronic …

IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation

A Ulu, S Sveiven, A Bilg, JV Velazquez, M Diaz… - Toxicology and applied …, 2022 - Elsevier
IL-22 is a unique cytokine that is upregulated in many chronic inflammatory diseases,
including asthma, and modulates tissue responses during inflammation. However, the role …

Omega-3 Fatty Acids and Chronic Lung Diseases: A Narrative Review of Impacts from Womb to Tomb

MJ Yaeger, L Leuenberger, SR Shaikh… - The Journal of Nutrition, 2024 - Elsevier
The lungs are a mucosal organ constantly exposed to potentially harmful compounds and
pathogens. Beyond their role in gas exchange, they must perform a well-orchestrated …

Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfα expression, gut barrier dysfunction, and endotoxemia in mice

MS Crawford, A Ulu, BM Ramirez… - American Journal …, 2024 - journals.physiology.org
Concentrated animal feeding operations (CAFOs) are responsible for the production of
global greenhouse gases and harmful environmental pollutants including hydrogen sulfide …

The potential role of n-3 fatty acids and their lipid mediators on asthmatic airway inflammation

Y Tian, JM Sun, DM Jiao, WY Zhang - Frontiers in Immunology, 2024 - frontiersin.org
Asthma, is a common, significant and diverse condition marked by persistent airway
inflammation, with a major impact on human health worldwide. The predisposing factors for …

Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand …

SN Sveiven, K Anesko, J Morgan, MG Nair… - International Journal of …, 2023 - mdpi.com
The role of pulmonary free fatty acid receptor 4 (FFAR4) is not fully elucidated and we aimed
to clarify the impact of FFAR4 on the pulmonary immune response and return to …