Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

Paracetamol (acetaminophen) is the most commonly used over‐the‐counter (OTC) drug in
the world. Despite its popularity and use for many years, the safety of its application and its …

Depression is the leading cause of disability worldwide. Recent observations have revealed
an association between mood disorders and alterations of the intestinal microbiota. Here …

The broad-based legalization of cannabis use has created a strong need to understand its
impact on human health and behavior. The risks that may be associated with cannabis use …

Ageing is characterized by the progressive impairment of physiological functions and
increased risk of developing debilitating disorders, including chronic inflammation and …

The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …

Cannabidiol (CBD), the main non-psychotomimetic component of the plant Cannabis sativa,
exerts therapeutically promising effects on human mental health such as inhibition of …

Endocannabinoids (eCBs) function as retrograde signaling molecules at synapses
throughout the brain, regulate axonal growth and guidance during development, and drive …