[HTML][HTML] CD4+ T cell memory
M Künzli, D Masopust - Nature immunology, 2023 - nature.com
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
T cells in health and disease
L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
[HTML][HTML] SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses
JS Turner, JA O'Halloran, E Kalaidina, W Kim… - Nature, 2021 - nature.com
Abstract SARS-CoV-2 mRNA-based vaccines are about 95% effective in preventing COVID-
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
M Gagne, JI Moliva, KE Foulds, SF Andrew, BJ Flynn… - Cell, 2022 - cell.com
SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
Cytokine regulation and function in T cells
C Dong - Annual review of immunology, 2021 - annualreviews.org
T lymphocytes, the major effector cells in cellular immunity, produce cytokines in immune
responses to mediate inflammation and regulate other types of immune cells. Work in the …
responses to mediate inflammation and regulate other types of immune cells. Work in the …
Germinal center and extrafollicular B cell responses in vaccination, immunity, and autoimmunity
RA Elsner, MJ Shlomchik - Immunity, 2020 - cell.com
Activated B cells participate in either extrafollicular (EF) or germinal center (GC) responses.
Canonical responses are composed of a short wave of plasmablasts (PBs) arising from EF …
Canonical responses are composed of a short wave of plasmablasts (PBs) arising from EF …
Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
Summary CD4 T follicular helper (TFH) cells support B cells, which are critical for germinal
center (GC) formation, but the importance of TFH-B cell interactions in cancer is unclear. We …
center (GC) formation, but the importance of TFH-B cell interactions in cancer is unclear. We …
Repositioning TH cell polarization from single cytokines to complex help
S Tuzlak, AS Dejean, M Iannacone, FJ Quintana… - Nature …, 2021 - nature.com
When helper T (TH) cell polarization was initially described three decades ago, the TH cell
universe grew dramatically. New subsets were described based on their expression of few …
universe grew dramatically. New subsets were described based on their expression of few …
Dendritic cell regulation of T helper cells
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
CD4 T helper cell subsets and related human immunological disorders
The immune system plays a critical role in protecting hosts from the invasion of organisms.
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …