Transposable phage mu
RM Harshey - Mobile DNA III, 2015 - Wiley Online Library
Transposable phage Mu has played a historic role in the development of the mobile DNA
element field (1). The very first paper that christened this phage after its mu tator properties …
element field (1). The very first paper that christened this phage after its mu tator properties …
[HTML][HTML] Characterization of a newly discovered Mu-like bacteriophage, RcapMu, in Rhodobacter capsulatus strain SB1003
The α-proteobacterium Rhodobacter capsulatus is a model organism for the study of
bacterial photosynthesis and the bacteriophage-like gene transfer agent. Characterization of …
bacterial photosynthesis and the bacteriophage-like gene transfer agent. Characterization of …
Separate structural and functional domains of Tn4430 transposase contribute to target immunity
Like other transposons of the Tn3 family, Tn4430 exhibits target immunity, a process that
prevents multiple insertions of the transposon into the same DNA molecule. Immunity is …
prevents multiple insertions of the transposon into the same DNA molecule. Immunity is …
Genomic, proteomic and bioinformatic analysis of two temperate phages in Roseobacter clade bacteria isolated from the deep-sea water
Background Marine phages are spectacularly diverse in nature. Dozens of roseophages
infecting members of Roseobacter clade bacteria were isolated and characterized …
infecting members of Roseobacter clade bacteria were isolated and characterized …
Transposable Prophage Mu Is Organized as a Stable Chromosomal Domain of E. coli
The E. coli chromosome is compacted by segregation into 400–500 supercoiled domains by
both active and passive mechanisms, for example, transcription and DNA-protein …
both active and passive mechanisms, for example, transcription and DNA-protein …
Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein
We describe a new immunity mechanism that protects actively replicating/transposing Mu
from self-integration. We show that this mechanism is distinct from the established cis …
from self-integration. We show that this mechanism is distinct from the established cis …
Analysis of phage Mu DNA transposition by whole-genome Escherichia coli tiling arrays reveals a complex relationship to distribution of target selection protein B …
Of all known transposable elements, phage Mu exhibits the highest transposition efficiency
and the lowest target specificity. In vitro, MuB protein is responsible for target choice. In this …
and the lowest target specificity. In vitro, MuB protein is responsible for target choice. In this …
Deep sequencing reveals new roles for MuB in transposition immunity and target-capture, and redefines the insular Ter region of E. coli
DM Walker, RM Harshey - Mobile DNA, 2020 - Springer
Background The target capture protein MuB is responsible for the high efficiency of phage
Mu transposition within the E. coli genome. However, some targets are off-limits, such as …
Mu transposition within the E. coli genome. However, some targets are off-limits, such as …
The N-terminal domain of MuB protein has striking structural similarity to DNA-binding domains and mediates MuB filament–filament interactions
M Dramićanin, B López-Méndez, J Boskovic… - Journal of structural …, 2015 - Elsevier
MuB is an ATP-dependent DNA-binding protein that regulates the activity of MuA
transposase and delivers the target DNA for transposition of phage Mu. Mechanistic insight …
transposase and delivers the target DNA for transposition of phage Mu. Mechanistic insight …
Mu Transposition in the Absence of the Target-capture Protein MuB Reveals New Roles of MuB in Target Immunity and Target Selection, and Redraws the Boundaries …
DM Walker, RM Harshey - bioRxiv, 2020 - biorxiv.org
The target capture protein MuB is responsible for the high efficiency of phage Mu
transposition within the E. coli genome. However, some targets are off-limits, such as …
transposition within the E. coli genome. However, some targets are off-limits, such as …