Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

Simple Summary Hypoxia is a common feature of solid tumors and associated with poor
outcome in most cancer types and treatment modalities, including radiotherapy …

Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

Inactivation of cancer stem cells (CSCs) is of utmost importance for tumor cure after
radiotherapy. An increasing body of evidence complies with a higher radioresistance of …

Oxygen deprivation (hypoxia) in non–small cell lung cancer (NSCLC) is an important factor
in treatment resistance and poor survival. Hypoxia is an attractive therapeutic target …

Radiomics applies machine learning algorithms to quantitative imaging data to characterise
the tumour phenotype and predict clinical outcome. For the development of radiomics risk …

Tumors are surrounded by complex environmental components, including blood and lymph
vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and …

Radiotherapy and radiation oncology play a key role in the clinical management of patients
suffering from oncological diseases. In clinical routine, anatomic imaging such as contrast …

Hypoxia is present to some extent in most solid malignant human cancers because of an
imbalance between the limited oxygen delivery capacity of the abnormal vasculature and …

Hypoxia is a pathological condition arising in living tissues when oxygen supply does not
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …