We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix,
where they interact with a plethora of ligands. Over the last decade, new insights have …

Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …

Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …

Myopia is of diverse aetiology. A small proportion of myopia is clearly familial, generally
early in onset and of high level, with defined chromosomal localisations and in some cases …

The collagen superfamily of proteins plays a dominant role in maintaining the integrity of
various tissues and also has a number of other important functions. The superfamily now …

Background Angiogenesis is the process of neovascularization from pre-existing
vasculature and is involved in various physiological and pathological processes. Inhibitors …

Left–right hemispheric asymmetry is an important aspect of healthy brain organization for
many functions including language, and it can be altered in cognitive and psychiatric …

The biology of basement membrane proteoglycans extends far beyond the original notion of
anionic filters. These complex molecules have dual roles as structural constituents of …

The cellular microenvironment, characterized by an extracellular matrix (ECM), played an
essential role in the transition from unicellularity to multicellularity in animals (metazoans) …