Human immunodeficiency virus (HIV) infection of the nervous system is unique when
compared with other viral encephalitides. Neuronal cell loss occurs in the absence of …

Many viruses have as part of their arsenal the ability to modulate the apoptotic pathways of
the host. It is counter-intuitive that such simple organisms would be efficient at regulating this …

Infection with the human immunodeficiency virus (HIV) is associated with a progressive
decrease in CD4 T-cell number and a consequent impairment in host immune defenses …

Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system (CNS)
causes AIDS dementia complex (ADC) in certain infected individuals. Recent studies have …

1. ABSTRACT Human immunodeficiency virus-1 (HIV-1) is the causative agent of acquired
immune deficiency syndrome (AIDS), a disease characterized by CD4+ T lymphocyte …

Infection with the human immunodeficiency virus type 1 (HIV-1) leads to progressive
immunodeficiency and onset of opportunistic infections and neoplasms. The loss of immune …

In contrast to insect viruses, animal viruses can produce considerable amounts of progeny
virus in cells undergoing apoptosis. Nevertheless, viruses in general have acquired the …

The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for
antiretroviral drug development. The conservation both of the structure along virus evolution …

Human immunodeficiency virus 1 (HIV-1) viral protein R (Vpr) has been shown to induce
host cell death by increasing the permeability of mitochondrial outer membrane (MOM). The …

Objective: Mitochondrial function plays a role in both AIDS progression and HAART toxicity;
therefore, we sought to determine whether mitochondrial DNA variation revealed novel AIDS …