T cell-mediated immunity to malaria
Immunity to malaria has been linked to the availability and function of helper CD4+ T cells,
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …
Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease
PD Crompton, J Moebius, S Portugal… - Annual review of …, 2014 - annualreviews.org
Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
[HTML][HTML] Gut microbiota elicits a protective immune response against malaria transmission
Glycosylation processes are under high natural selection pressure, presumably because
these can modulate resistance to infection. Here, we asked whether inactivation of the UDP …
these can modulate resistance to infection. Here, we asked whether inactivation of the UDP …
[HTML][HTML] Common PIEZO1 allele in African populations causes RBC dehydration and attenuates plasmodium infection
Hereditary xerocytosis is thought to be a rare genetic condition characterized by red blood
cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced …
cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced …
CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications
C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10kDa (IP-
10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family …
10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family …
Immunological processes in malaria pathogenesis
L Schofield, GE Grau - Nature Reviews Immunology, 2005 - nature.com
Malaria is possibly the most serious infectious disease of humans, infecting 5–10% of the
world's population, with 300–600 million clinical cases and more than 2 million deaths …
world's population, with 300–600 million clinical cases and more than 2 million deaths …
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
Cerebral malaria claims more than 1 million lives per year. We report that heme oxygenase-
1 (HO-1, encoded by Hmox1) prevents the development of experimental cerebral malaria …
1 (HO-1, encoded by Hmox1) prevents the development of experimental cerebral malaria …
Severe malaria infections impair germinal center responses by inhibiting T follicular helper cell differentiation
V Ryg-Cornejo, LJ Ioannidis, A Ly, CY Chiu, J Tellier… - Cell reports, 2016 - cell.com
Naturally acquired immunity to malaria develops only after years of repeated exposure to
Plasmodium parasites. Despite the key role antibodies play in protection, the cellular …
Plasmodium parasites. Despite the key role antibodies play in protection, the cellular …
[HTML][HTML] Sickle hemoglobin confers tolerance to Plasmodium infection
Sickle human hemoglobin (Hb) confers a survival advantage to individuals living in endemic
areas of malaria, the disease caused by Plasmodium infection. As demonstrated hereby …
areas of malaria, the disease caused by Plasmodium infection. As demonstrated hereby …
Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatment
X Song, W Wei, W Cheng, H Zhu, W Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological
complication of malaria, resulting in coma and death, and even survivors may suffer long …
complication of malaria, resulting in coma and death, and even survivors may suffer long …