Neutrophils and polymorphonuclear myeloid-derived suppressor cells: an emerging battleground in cancer therapy

H Raskov, A Orhan, S Gaggar, I Gögenur - Oncogenesis, 2022 - nature.com
Neutrophils are central mediators of innate and adaptive immunity and first responders to
tissue damage. Although vital to our health, their activation, function, and resolution are …

Clinical impact of nutrition and inflammation assessment tools in pancreatic cancer treatment

T Aoyama, Y Maezawa, I Hashimoto, Y Rino… - Anticancer …, 2023 - ar.iiarjournals.org
Perioperative adjuvant treatment and complete resection is the standard treatment for
resectable pancreatic cancer and systemic chemotherapy is standard treatment for …

Effect of a MUC5AC antibody (NPC-1C) administered with second-line gemcitabine and nab-paclitaxel on the survival of patients with advanced pancreatic ductal …

BM Huffman, AB Mallick, NK Horick… - JAMA network …, 2023 - jamanetwork.com
Importance Treatment options are limited for patients with advanced pancreatic ductal
adenocarcinoma (PDAC) beyond first-line 5-fluorouracil, leucovorin, irinotecan, and …

The prognostic and predictive role of the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) as …

S Maloney, N Pavlakis, M Itchins, J Arena… - Journal of Clinical …, 2023 - mdpi.com
Pancreatic cancer has poor survival despite modern-day advances in its management. At
present, there are no available biomarkers that can predict chemotherapy response or help …

Leveling up the controversial role of neutrophils in cancer: when the complexity becomes entangled

RV Sionov - Cells, 2021 - mdpi.com
Neutrophils are the most abundant immune cell in the circulation of human and act as
gatekeepers to discard foreign elements that have entered the body. They are essential in …

Clinical Value of Circulating miRNA in Diagnosis, Prognosis, Screening and Monitoring Therapy of Pancreatic Ductal Adenocarcinoma—A Review of the Literature

J Wnuk, JK Strzelczyk, I Gisterek - International Journal of Molecular …, 2023 - mdpi.com
Pancreatic cancer (PC) is considered to be the seventh most common cause of cancer-
related deaths. The number of deaths caused by PC is estimated to increase in the future …

[HTML][HTML] Artificial intelligence-based comprehensive analysis of immune-stemness-tumor budding profile to predict survival of patients with pancreatic adenocarcinoma

T Zhou, Q Man, X Li, Y Xie, X Hou, H Wang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Objective: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy. CD8+ T
cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated …

[HTML][HTML] Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of …

JB Permuth, MA Park, DT Chen, T Basinski… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives The main objective of this study was to determine the prevalence of CC stage
overall and by sex and race and ethnicity among treatment-naïve PDAC cases using clinical …

Prognostic value of preoperative NLR and vascular reconstructive technology in patients with pancreatic cancer of portal system invasion: a real world study

L Zhou, J Wang, X Zhang, S Lyu, L Pan, G Du… - Frontiers in …, 2021 - frontiersin.org
The purpose was aimed to establish a simple computational model to predict tumor
prognosis by combining neutrophil to lymphocyte Ratio (NLR) and biomarkers of …

[Retracted] Correlation Between Platelet‐Lymphocyte Ratio and Neutrophil‐Lymphocyte Ratio in Patients with Uterine Leiomyoma: A Cross‐Sectional Study

Y Duan, Y Peng, X Shi, Y Zhao, K Liu… - Journal of …, 2022 - Wiley Online Library
The inflammatory reaction has been proven to be a key factor in the pathogenesis of uterine
leiomyoma. The platelet‐lymphocyte ratio (PLR) and the neutrophil‐lymphocyte ratio (NLR) …