[HTML][HTML] Role of neuroinflammation in neurodegeneration development

W Zhang, D Xiao, Q Mao, H Xia - Signal transduction and targeted …, 2023 - nature.com
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

[HTML][HTML] Role of Microglia and Astrocytes in Alzheimer's Disease: From Neuroinflammation to Ca2+ Homeostasis Dysregulation

G Di Benedetto, C Burgaletto, CM Bellanca, A Munafò… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

[HTML][HTML] Astrocytes as a therapeutic target in alzheimer's disease–comprehensive review and recent developments

M Rodríguez-Giraldo, RE González-Reyes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

[HTML][HTML] Amyloid-β specific regulatory T cells attenuate Alzheimer's disease pathobiology in APP/PS1 mice

P Yeapuri, J Machhi, Y Lu, MM Abdelmoaty… - Molecular …, 2023 - Springer
Abstract Background Regulatory T cells (Tregs) maintain immune tolerance. While Treg-
mediated neuroprotective activities are now well-accepted, the lack of defined antigen …

[HTML][HTML] Emerging roles of cells and molecules of innate immunity in Alzheimer's disease

B Tamburini, GD Badami, MP La Manna… - International journal of …, 2023 - mdpi.com
The inflammatory response that marks Alzheimer's disease (neuroinflammation) is
considered a double-edged sword. Microglia have been shown to play a protective role at …

Targeting gut microbiota to alleviate neuroinflammation in Alzheimer's disease

VTT Nguyen, K Endres - Advanced drug delivery reviews, 2022 - Elsevier
The gut microbiota came into focus within the last years regarding being associated with or
even underlying neuropsychiatric diseases. The existence of the gut-brain-axis makes it …

[HTML][HTML] Single-cell and single-nuclei RNA sequencing as powerful tools to decipher cellular heterogeneity and dysregulation in neurodegenerative diseases

R Cuevas-Diaz Duran, JC González-Orozco… - Frontiers in Cell and …, 2022 - frontiersin.org
Neurodegenerative diseases affect millions of people worldwide and there are currently no
cures. Two types of common neurodegenerative diseases are Alzheimer's (AD) and …

[HTML][HTML] Iron chelators as a therapeutic option for Alzheimer's disease—A mini-review

OD Schreiner, TG Schreiner - Frontiers in Aging, 2023 - frontiersin.org
Neurodegenerative disorders, particularly Alzheimer's disease (AD), remain a great
challenge regarding the finding of effective treatment, one main reason being the incomplete …

[HTML][HTML] Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting

X Zeng, Y Chen, A Sehrawat, J Lee, TK Lafferty… - Molecular …, 2024 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, remains challenging
to understand and treat despite decades of research and clinical investigation. This might be …

[HTML][HTML] The therapeutic and diagnostic potential of amyloid β oligomers selective antibodies to treat Alzheimer's disease

KL Viola, MA Bicca, AM Bebenek, DL Kranz… - Frontiers in …, 2022 - frontiersin.org
Improvements have been made in the diagnosis of Alzheimer's disease (AD), manifesting
mostly in the development of in vivo imaging methods that allow for the detection of …