Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

Soluble sugars serve five main purposes in multicellular organisms: as sources of carbon
skeletons, osmolytes, signals, and transient energy storage and as transport molecules …

Absorption of monosaccharides is mainly mediated by Na+-d-glucose cotransporter SGLT1
and the facititative transporters GLUT2 and GLUT5. SGLT1 and GLUT2 are relevant for …

Increased sugar consumption is increasingly considered to be a contributor to the worldwide
epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of …

The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …

Glucose is the major energy source for mammalian cells as well as an important substrate
for protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into …

Glucose is the principle energy source for the mammalian brain. Delivery of glucose from the
blood to the brain requires transport across the endothelial cells of the blood‐brain barrier …

The altered activity of the fructose transporter GLUT5, an isoform of the facilitated-diffusion
glucose transporter family, has been linked to disorders such as type 2 diabetes and obesity …

Fructose is now such an important component of human diets that increasing attention is
being focused on the fructose transporter GLUT5. In this review, we describe the regulation …