Viral vectors are poised to acquire a prominent position in modern medicine and
biotechnology owing to their role as delivery agents for gene therapies, oncolytic agents …

Abstract Chinese Hamster Ovary (CHO) cells, employed primarily for manufacturing
monoclonal antibodies and other recombinant protein (r-protein) therapeutics, are emerging …

The recent uptick in the approval of ex vivo cell therapies highlights the relevance of
lentivirus (LV) as an enabling viral vector of modern medicine. As labile biologics, however …

This work aimed to quantify growth and biochemical parameters (viable cell density, Xv; cell
viability, CV; glucose, lactate, glutamine, glutamate, ammonium, and potassium …

Chimeric virus-like particles formed by the co-expression of HIV-1 gag capsid protein and
surface proteins from other viruses can be used as a platform for production of a wide range …

The use of viral vectors as therapeutic products for multiple applications such as vaccines,
cancer treatment, or gene therapies, has been growing exponentially. Therefore, improved …

High Five cells are an excellent host for the production of virus-like particles (VLPs) with the
baculovirus expression vector system (BEVS). However, the concurrent production of high …

Extracellular vesicles (EVs) have emerged as promising therapeutics with broad clinical
applications as diagnostic biomarkers and therapeutic drug delivery systems. Yet, these …

Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine
candidates. Nonetheless, their characterization is challenging due to VLPs' unique …

Virus-like particles (VLPs) resemble the viral native conformation by the recombinant
expression of their structural proteins. Their highly organized and repetitive structure has …