The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

OBJECTIVE We examined changes in glucose-lowering medication spending and
quantified the magnitude of factors that are contributing to these changes. RESEARCH …

Medicine should ideally be personalized as each individual has his/her own unique
biological, physical, and medical dispositions. Medicine can be personalized by customizing …

Importance Accelerated approval by the US Food and Drug Administration (FDA) grants
market authorization for drugs based on clinical trials using surrogate end points likely to …

Medication adherence is a well-known problem for pharmaceutical treatment of chronic
diseases. Understanding how nonadherence affects treatment efficacy is made difficult by …

Importance New formulations of prescription drugs can improve convenience and tolerability
for patients, but they also constitute manufacturer strategies to extend brand-name drug …

Physicians commonly receive marketing-related transfers from drug firms. We examine the
impact of these relationships on the prescribing of physician-administered cancer drugs in …

2. Methods We included the 20 oral anticancer drugs with the highest spending in Medicare
Part D in 2020, used by 323,478 beneficiaries [4]. For each drug, we identified formulations …

Many drugs come in two forms, immediate—release and extended—release, that are
differentiated by the way the drug is released. Immediate—released formulations of drugs …

Switching from extended-release (ER) to immediate-release (IR) formulations for therapeutic
equivalent drugs may offer the potential to reduce Medicaid and Medicare spending in the …