Mild cognitive impairment is a well-documented consequence of whole brain radiation
therapy (WBRT) that affects 40-50% of long-term brain tumor survivors. The exact …

Whole brain radiation therapy (WBRT) is commonly used for treatment of primary and
metastatic brain tumors; however, cognitive impairment occurs in 40–50% of brain tumor …

Apoptosis, known as programmed cell death, plays a crucial role in normal development
and tissue homeostasis. Apoptosis is also involved in neurodegenerative diseases such as …

Currently, NASA has plans for extended space travel, and previous research indicates that
space radiation can have negative effects on cognitive skills as well as physical and mental …

The effect of acute irradiation with 5 Gy or fractionated exposure with 0.5 Gy continuously for
10 days (a total dose of 5 Gy) was evaluated in an immature BALB/c mouse model …

Results: Our results showed that the number of neurons in all experimental groups was
lower than that in the control group. The highest decrease in number of neurons was shown …

Radiotherapy is routinely used for the treatment of nearly all brain tumors, but it may lead to
progressive and debilitating impairments of cognitive function. The growing evidence …

The effect of acute X-ray irradiation with 2 Gy or fractionated exposure with 0.2 Gy
continuously for 10 days (0.2 Gy× 10= 2 Gy) was evaluated in the postnatal day 21 (P21) …

Cholinergic system in CNS is involved in learning and memory. Scopolamine as muscarinic
acetylcholine receptor antagonist is used for creation of memory impairment. The purpose of …

Methods: Morphine (10 mg/kg, IP) was injected in male Wistar rats for 7 consecutive days
(intervention group), but control rats received just normal saline (1 mL/kg, IP). We used a …