Tracking the biogeochemical behavior of tire wear particles in the environment-A review

Q Xu, SSUH Kazmi, G Li - Journal of Hazardous Materials, 2024 - Elsevier
The environmental fate and risks associated with tire wear particles (TWPs) are closely
linked to their biogeochemical behaviors. However, reviews that focus on TWPs from this …

[HTML][HTML] Neurotoxicity from long-term exposure to 6-PPDQ: Recent advances

CS Ma, DL Li, F Wang, JP Wang, MT He - … and Environmental Safety, 2024 - Elsevier
The recent acceleration of industrialization and urbanization has brought significant
attention to N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6-PPDQ), an …

Distinct Species-Specific and Toxigenic Metabolic Profiles for 6PPD and 6PPD Quinone by P450 Enzymes: Insights from In Vitro and In Silico Studies

Z Song, X Yu, M Zhu, Z Wu, Z Fu… - Environmental Science & …, 2024 - ACS Publications
The tire rubber antioxidant N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD)
and its quinone product (6PPDQ) are prevalent emerging contaminants, yet their …

[HTML][HTML] Tire-derived contaminants 6PPD and 6PPD-Q: Analysis, sample handling, and reconnaissance of United States stream exposures

RF Lane, KL Smalling, PM Bradley, JB Greer… - Chemosphere, 2024 - Elsevier
The environmental ubiquity of tire and road wear particles (TRWP) underscores the need to
understand the occurrence, persistence, and environmental effects of tire-related chemicals …

Environmental concentrations of 6PPD and 6PPD-Q cause oxidative damage and alter metabolism in Eichhornia crassipes

Y Ge, J Liu, R Shi, X Li, A Zeb, Q Wang, J Wang… - Science of The Total …, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and N-(1, 3-
dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q) are ubiquitous in the …

Characterizing the Metabolism of Tire Rubber-Derived p-Phenylenediamine Quinones to Identify Potential Exposure Biomarkers in Humans

Y Yang, W Meng, Y Zhang, W Meng, J Li… - Environmental …, 2024 - ACS Publications
There is growing evidence of the frequent detection of tire rubber-derived contaminants p-
phenylenediamine-derived quinones (PPD-Qs)(eg, highly toxic N-(1, 3-dimethylbutyl)-N …

Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insights

W Wang, Y Chen, J Fang, F Zhang, G Qu… - Journal of Hazardous …, 2024 - Elsevier
Substituted para-phenylenediamines (PPDs) are synthetic chemicals used globally for
rubber antioxidation, with their quinone derivatives (PPD-Qs) raising particular …

[HTML][HTML] Environmental profiles, hazard identification, and toxicological hallmarks of emerging tire rubber-related contaminants 6PPD and 6PPD-quinone

Y Jiang, C Wang, L Ma, T Gao, Y Wāng - Environment International, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is commonly used in
rubber compounds as antioxidants to protect against degradation from heat, oxygen, and …

[HTML][HTML] A bibliometric analysis of global research hotspots and progress on emerging environmental pollutants 6PPD and 6PPD-quinone from 2004 to 2024

S Babaei, F Reguyal, AK Sarmah - Environmental Pollution, 2024 - Elsevier
Abstract The emerging toxicants, N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine
quinone (6PPD-Q), resulting from environmental exposure to N-(1, 3-dimethylbutyl)-N' …

[HTML][HTML] Paeoniflorin alleviates toxicity and accumulation of 6-PPD quinone by activating ACS-22 in Caenorhabditis elegans

M Song, Q Ruan, D Wang - Ecotoxicology and Environmental Safety, 2024 - Elsevier
PPD quinone (6-PPDQ) is extensively existed in various environments. In Caenorhabditis
elegans, exposure to 6-PPDQ could cause multiple toxic effects. In the current study, we …