Ischaemia‐reperfusion injury is a complex phenomenon often encountered in surgical
practice. The consequences of such injury are local and remote tissue destruction, and …

Ischaemia is a common clinical event leading to local and remote injury. Evidence indicates
that tissue damage is largely caused by activated neutrophils which accumulate when the …

Platelets exhibit archetypal structures and functions enabling their roles as multifunctional
host defense cells. Beyond roles in hemostasis and wound repair, platelets sense and …

The term ischemia-reperfusion injury describes the experimentally and clinically prevalent
finding that tissue ischemia with inadequate oxygen supply followed by successful …

ASTHMA is characterized by Variable and reversible airflow obstruction and by bronchial
hyper-responsiveness, an excessive airway narrowing in response to a variety of apparently …

The treatment of septic shock remains a major problem in surgical practice. Current research
on the pathogenesis of the sepsis syndrome focuses on the effects of the lipopolysaccharide …

Eicosanoids are modulators of defensive and inflammatory processes in the gut mucosa,
and may be involved in the pathogenesis of chronic inflammatory lesions of the bowel. As …

Arachidonic acid metabolism plays an important role in acute ischemic syndromes affecting
the coronary or cerebrovascular territory, as reflected by biochemical measurements of …

Current dogma holds that nonsteroidal anti-inflammatory drugs (NSAIDs) act by inhibition of
the synthesis and release of prostaglandins. However, NSAIDs also inhibit the activation of …

Lower torso ischemia leads on reperfusion to sequestration of polymorphonuclear
leukocytes (PMN) in the lungs and increased permeability. This study tests the role of …