A review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone, a naturally-occurring biflavonoid

S Yu, H Yan, L Zhang, M Shan, P Chen, A Ding, SFY Li - Molecules, 2017 - mdpi.com
Amentoflavone (C30H18O10) is a well-known biflavonoid occurring in many natural plants.
This polyphenolic compound has been discovered to have some important bioactivities …

Pharmacogenomics of Alzheimer's disease: Novel therapeutic strategies for drug development

R Cacabelos, P Cacabelos, C Torrellas… - … in Drug Discovery and …, 2014 - Springer
Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …

Scopolamine promotes neuroinflammation and delirium-like neuropsychiatric disorder in mice

SY Cheon, BN Koo, SY Kim, EH Kam, J Nam, EJ Kim - Scientific reports, 2021 - nature.com
Postoperative delirium is a common neuropsychiatric syndrome resulting a high postsurgical
mortality rate and decline in postdischarge function. Extensive research has been performed …

A Comparative Bio-Evaluation and Chemical Profiles of Calendula officinalis L. Extracts Prepared via Different Extraction Techniques

G Ak, G Zengin, KI Sinan, MF Mahomoodally… - Applied sciences, 2020 - mdpi.com
Featured Application This study provides valuable data on the influence of extraction
techniques on the recovery of bioactive compounds from Calendula officinalis useful for the …

Protective effect of alpha mangostin on rotenone induced toxicity in rat model of Parkinson's disease

A Parkhe, P Parekh, LV Nalla, N Sharma, M Sharma… - Neuroscience …, 2020 - Elsevier
Parkinson's disease (PD) is a progressive, late-onset, and degenerative disorder that affects
the central nervous system with an unknown etiology. Due to its incredible complexity in …

The Potential Neuroprotective Effect of Cyperus esculentus L. Extract in Scopolamine-Induced Cognitive Impairment in Rats: Extensive Biological and Metabolomics …

MM Saeed, Á Fernández-Ochoa, FR Saber, RH Sayed… - Molecules, 2022 - mdpi.com
The aim of the present study is to investigate the phytochemical composition of tiger nut
(TN)(Cyperus esculentus L.) and its neuroprotective potential in scopolamine (Scop) …

Medicinal plants with acetylcholinesterase inhibitory activity

SS Patel, R Raghuwanshi, M Masood… - Reviews in the …, 2018 - degruyter.com
Alzheimer's disease, a progressive neurodegenerative disease, is characterised by
hypofunction of acetylcholine (ACh) neurotransmitter in the distinct region of brain …

Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic …

IO Ishola, AA Jacinta, OO Adeyemi - Metabolic Brain Disease, 2019 - Springer
Alzheimer disease (AD) is an age related neurodegenerative disease causing severe
cognitive and memory decline in elderly people. Flavonoids play neuroprotective role by …

Effect of Sanguisorba minor on scopolamine-induced memory loss in rat: involvement of oxidative stress and acetylcholinesterase

Z Hosseini, F Mansouritorghabeh, FSH Kakhki… - Metabolic Brain …, 2022 - Springer
Sanguisorba minor (S. minor) has neuroprotective and antioxidant activities. However, its
potential benefits in ameliorating learning and memory functions have been explored in no …

Ameliorative effect of kolaviron, a biflavonoid complex from Garcinia kola seeds against scopolamine-induced memory impairment in rats: role of antioxidant defense …

IO Ishola, FM Adamson, OO Adeyemi - Metabolic brain disease, 2017 - Springer
In Alzheimer's disease (AD) basal forebrain cholinergic neurons appear to be targeted
primarily in early stages of the disease. Scopolamine (muscarinic receptor antagonist) has …