Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …

A legacy of molecular evolution is the formation of gene families encoding proteins that often
serve related functions. One such family gaining recent attention is the tetraspanin …

Recently, we found that ZO-1, a tight junction-associated protein, was concentrated in the so
called isolated adherens junction fraction from the liver (Itoh, M., A. Nagafuchi, S. Yonemura …

Exosomes are natural nanoparticles that play an important role in cell-to-cell
communication. Communication is achieved through the transfer of cargos, such as …

A gene from human chromosome 11p11. 2 was isolated and was shown to suppress
metastasis when introduced into rat AT6. 1 prostate cancer cells. Expression of this gene …

High expression of EpCAM and the tetraspanin CO-029 has been associated with colorectal
cancer progression. However, opposing results have been reported on CD44 variant …

Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …

Structural characterization of biomolecules in solution by nuclear magnetic resonance
(NMR) spectroscopy is based primarily on the use of interproton distances derived from …

The role of transmembrane 4 superfamily (TM4SF) proteins during muscle cell fusion has
not been investigated previously. Here we show that the appearance of TM4SF protein …

CD151 is a cell surface protein that belongs to the tetraspan superfamily. It associates with
other tetraspan molecules and certain integrins to form large complexes at the cell surface …