Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

A nanobody (Nb) is a registered trademark of Ablynx, referring to the single antigen‐binding
domain of heavy chain‐only antibodies (HCAbs) that are circulating in Camelidae. Nbs are …

Abstract Machine learning-based models of protein fitness typically learn from either
unlabeled, evolutionarily related sequences or variant sequences with experimentally …

A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …

In this review, we detail the efforts performed to couple the purification and the
immobilization of industrial enzymes in a single step. The use of antibodies, the …

Reproducibility: Standardize antibodies used in research | Nature Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

The robust, sensitive, and selective detection of targeted biomolecules in their native
environment by prospective nanostructures holds much promise for real-time, accurate, and …

Interrogation of the human proteome in a highly multiplexed and efficient manner remains a
coveted and challenging goal in biology. We present a new aptamer-based proteomic …

Limited chemical diversity of nucleic acid libraries has long been suspected to be a major
constraining factor in the overall success of SELEX (Systematic Evolution of Ligands by …

Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …