Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry

C Vicente-Garcia, I Colomer - Nature Reviews Chemistry, 2023 - nature.com
Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C
or N terminus of peptides. Their self-assembly—into micelles, vesicles, nanotubes, fibres or …

Biodegradable cationic and ionizable cationic lipids: A roadmap for safer pharmaceutical excipients

AM Jörgensen, R Wibel, A Bernkop‐Schnürch - Small, 2023 - Wiley Online Library
Cationic and ionizable cationic lipids are broadly applied as auxiliary agents, but their use is
associated with adverse effects. If these excipients are rapidly degraded to endogenously …

Conjugation of antimicrobial peptides to enhance therapeutic efficacy

SP Selvaraj, JY Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Biomimetic peptoid-assisted fabrication of antibiofouling thin-film composite membranes

SJ Park, MS Lee, H Yoon, JH Kim, S Jeon… - Chemical Engineering …, 2023 - Elsevier
Polyamide (PA) thin-film composite (TFC) membranes are extensively used in water
purification but suffer from chronic biofouling, which has spurred extensive research on the …

[HTML][HTML] Lipopeptides development in cosmetics and pharmaceutical applications: a comprehensive review

M Pilz, P Cavelius, F Qoura, D Awad, T Brück - Biotechnology Advances, 2023 - Elsevier
Lipopeptides are surface active, natural products of bacteria, fungi and green-blue algae
origin, having diverse structures and functionalities. In analogy, a number of chemical …

Lipidated analogs of the LL-37-derived peptide fragment KR12—structural analysis, surface-active properties and antimicrobial activity

E Kamysz, E Sikorska, M Jaśkiewicz, M Bauer… - International journal of …, 2020 - mdpi.com
An increasing number of multidrug-resistant pathogens is a serious problem of modern
medicine and new antibiotics are highly demanded. In this study, different n-alkyl acids (C2 …

Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Ultra-short lipopeptides against gram-positive bacteria while alleviating antimicrobial resistance

C Zhong, F Zhang, N Zhu, Y Zhu, J Yao, S Gou… - European Journal of …, 2021 - Elsevier
Facing the continuously urgent demands for novel antimicrobial agents since the growing
emergence of bacterial resistance, a series of new ultra-short lipopeptides, composed of …

Lipidation of antimicrobial peptides as a design strategy for future alternatives to antibiotics

T Rounds, SK Straus - International Journal of Molecular Sciences, 2020 - mdpi.com
Multi-drug-resistant bacteria are becoming more prevalent, and treating these bacteria is
becoming a global concern. One alternative approach to combat bacterial resistance is to …

Rational Design and Antimicrobial Potency Assessment of Abaecin Analogues

J Yang, P Wu, Y Weng, Y Lin, Z Chen… - ACS Biomaterials …, 2023 - ACS Publications
The widespread and escalating emergence of multidrug resistance is now recognized as
one of the most severe global threats to human health. To address the urgent issue of drug …