Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation

KR Dunning, DL Russell, RL Robker - Reproduction, 2014 - research.monash.edu
Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …

Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

Melatonin inhibits apoptosis and improves the developmental potential of vitrified bovine oocytes

XM Zhao, HS Hao, WH Du, SJ Zhao… - Journal of pineal …, 2016 - Wiley Online Library
Vitrification of oocytes has been shown to be closely associated with increased levels of
reactive oxygen species (ROS) and apoptotic events. However, little information is available …

Changes in mitochondrial function in porcine vitrified MII-stage oocytes and their impacts on apoptosis and developmental ability

J Dai, C Wu, CW Muneri, Y Niu, S Zhang, R Rui… - Cryobiology, 2015 - Elsevier
The purpose of this study was to investigate the changes in mitochondria in porcine MII-
stage oocytes after open pulled straw (OPS) vitrification and to determine their roles in …

Biological roles of l‐carnitine in oocyte and early embryo development

J Li, L Liu, J Weng, T Yin, J Yang… - Molecular Reproduction …, 2021 - Wiley Online Library
Poor oocyte quality is responsible for female infertility. Multiple studies have been carried
out to find supplements to enhance oocyte quality and mitigate infertility problems. l …

[PDF][PDF] Fatty acid metabolism during maturation affects glucose uptake and is essential to oocyte competence

M Paczkowski, WB Schoolcraft, RL Krisher - Reproduction, 2014 - scholar.archive.org
Fatty acid b-oxidation (FAO) is essential for oocyte maturation in mice. The objective of this
study was to determine the effect of etomoxir (a FAO inhibitor; 100 mM), carnitine (1 mM) …

Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification

D Lai, J Ding, GW Smith, GD Smith… - Human …, 2015 - academic.oup.com
STUDY QUESTION Does the use of a new cryoprotectant agent (CPA) exchange protocol
designed to minimize osmotic stress improve oocyte or zygote vitrification by reducing …

Cryopreservation of mammalian oocytes and embryos: current problems and future perspectives

M Moussa, J Shu, XH Zhang, FY Zeng - Science China Life Sciences, 2014 - Springer
Cryopreservation techniques for mammalian oocytes and embryos have rapidly progressed
during the past two decades, emphasizing their importance in various assisted reproductive …

Effects of β-nicotinamide mononucleotide, berberine, and cordycepin on lipid droplet content and developmental ability of vitrified bovine oocytes

X Xu, B Yang, H Zhang, X Feng, H Hao, W Du, H Zhu… - Antioxidants, 2023 - mdpi.com
Oocyte vitrification is crucial for livestock reproduction, germplasm conservation, and human-
assisted reproduction, but the overabundance of lipids is highly detrimental to oocyte …

l-carnitine supplementation during vitrification of mouse germinal vesicle stage–oocytes and their subsequent in vitro maturation improves meiotic spindle …

AR Moawad, B Xu, SL Tan, T Taketo - Human reproduction, 2014 - academic.oup.com
STUDY QUESTION How does l-carnitine (LC) supplementation during vitrification and in
vitro maturation (IVM) of germinal vesicle stage (GV)–oocytes improve the developmental …