Essentially all cortical areas receive thalamic inputs and send outputs to lower motor
centers. Cortical areas communicate with each other by means of direct corticocortical and …

The thalamus is the major source of cortical inputs shaping sensation, action, and cognition.
Thalamic circuits are targeted by two major inhibitory systems: the thalamic reticular nucleus …

Subdivisions of mouse whisker somatosensory thalamus project to cortex in a region-
specific and layer-specific manner. However, a clear anatomical dissection of these …

The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …

The rodent whisker system is widely used as a model system for investigating sensorimotor
integration, neural mechanisms of complex cognitive tasks, neural development, and …

Layer (L) 2/3 pyramidal neurons in the primary somatosensory cortex (S1) are sparsely
active, spontaneously and during sensory stimulation. Long-range inputs from higher areas …

We now know that sensory processing in cortex occurs not only via direct communication
between primary to secondary areas, but also via their parallel cortico-thalamo-cortical (ie …

What any sensory neuron knows about the world is one of the cardinal questions in
Neuroscience. Information from the sensory periphery travels across synaptically coupled …

Central pain syndrome (CPS) is a debilitating condition that affects a large number of
patients with a primary lesion or dysfunction in the CNS. Despite its discovery over a century …

The zona incerta (ZI) is a subthalamic region composed by loosely packed neurochemically
mixed neurons, juxtaposed to the main ascending and descending bundles. The extreme …