Multi-chain chimeric polypeptides and uses thereof

H Wong - US Patent 11,518,792, 2022 - Google Patents
C07K16/283—Immunoglobulins [IGs], eg monoclonal or polyclonal antibodies against
material from animals or humans against receptors, cell surface antigens or cell surface …

Methods of treating age-related and inflammatory diseases

HC Wong - US Patent 12,115,191, 2024 - Google Patents
UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2= CC
(= O) C= C [C@] 2 (C)[C@] 2 (F)[C@@ H] 1 [C@@ H] 1C [C@@ H](C)[C@@](C (= O) …

Methods of treating aging-related disorders

HC Wong, X Zhu, B Liu, P Chaturvedi… - US Patent …, 2024 - Google Patents
US12024545B2 - Methods of treating aging-related disorders - Google Patents US12024545B2
- Methods of treating aging-related disorders - Google Patents Methods of treating aging-related …

Immune cells expressing engineered antigen receptors

K Rezvani, EJ Shpall - US Patent 11,344,578, 2022 - Google Patents
US11344578B2 - Immune cells expressing engineered antigen receptors - Google Patents
US11344578B2 - Immune cells expressing engineered antigen receptors - Google Patents …

Multi-chain chimeric polypeptides and uses thereof

HC Wong - US Patent 11,738,052, 2023 - Google Patents
The present disclosure relates to methods that include the use of a first multi-chain chimeric
polypeptide and a second multi-chain chimeric polypeptide for stimulating the NK cells …

Single-chain chimeric polypeptides and uses thereof

H Wong - US Patent 11,401,324, 2022 - Google Patents
Provided herein are single-chain chimeric polypeptides that include:(i) a first target-binding
domain;(ii) a soluble tissue factor domain; and (iii) a second target-binding domain. Also …

Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents

MC Jensen, J Matthaei - US Patent 11,649,288, 2023 - Google Patents
TZCPCKNHXULUIY-RGULYWFUSA-N 1, 2-distearoyl-sn-glycero-3-phosphoserine
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(= O) OC [C …

Methods of use for CAR T cells

MC Jensen, J Matthaei - US Patent 11,311,576, 2022 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

Single-chain chimeric polypeptides and uses thereof

H Wong - US Patent 12,018,071, 2024 - Google Patents
Provided herein are single-chain chimeric polypeptides that include:(i) a first target-binding
domain;(ii) a soluble tissue factor domain; and (iii) a second target-binding domain. Also …

Methods of treating aging-related disorders

H Wong - US Patent 11,672,826, 2023 - Google Patents
BGFTWECWAICPDG-UHFFFAOYSA-N 2-[bis (4-chlorophenyl) methyl]-4-n-[3-[bis (4-
chlorophenyl) methyl]-4-(dimethylamino) phenyl]-1-n, 1-n-dimethylbenzene-1, 4-diamine …