The development of resistome analysis, ie the comprehensive analysis of antibiotic-
resistance genes (ARGs), is enabling a better understanding of the mechanisms of antibiotic …

Background Gut microbial diversity is associated with improved response to immune
checkpoint inhibitors (ICI). Based on the known detrimental impact that antibiotics have on …

Environmental antibiotic resistance genes (ARGs) have received much attention, while the
characteristics of ARGs carried by particulate matter (PM) as a function of urban functional …

Antibiotic therapy is one of the main treatments for cystic fibrosis (CF). It aims to eradicate
bacteria during early infection, calms down the inflammatory process, and leads to symptom …

Assessing the taxonomic composition of metagenomic samples is an important first step in
understanding the biology and ecology of microbial communities in complex environments …

The identification of 16S rDNA biomarkers from respiratory samples to describe the
continuum of clinical disease states within persons having cystic fibrosis (CF) has remained …

Introduction Pulmonary exacerbations (PEx) in persons with cystic fibrosis (CF) are primarily
related to acute or chronic inflammation associated with bacterial lung infections, which may …

Chronic (long-lasting) infections are globally a major and rising cause of morbidity and
mortality. Unlike typical acute infections, chronic infections are ecologically diverse …

Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease
and the third leading cause of death worldwide. Developments in next-generation …

The advent of next generation sequencing has rapidly challenged the paediatric respiratory
physician's understanding of lung microbiology and the role of the lung microbiome in host …