The use of enzymes in industrial processes requires the improvement of their features in
many instances. Enzyme immobilization, a requirement to facilitate the recovery and reuse …

Engineered thermostable microbial enzymes are widely employed to catalyze chemical
reactions in numerous industrial sectors. Although high thermostability is a prerequisite of …

Unusual amino acids are fundamental building blocks of modern medicinal chemistry. The
combination of readily functionalized amine and carboxyl groups attached to a chiral central …

The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …

Improvement in intrinsic enzymatic features is in many instances a prerequisite for the
scalable applicability of many industrially important biocatalysts. To this end, various …

Unnatural amino acids have gained significant attention in protein engineering and drug
discovery as they allow the evolution of proteins with enhanced stability and activity. The …

A protocol for stereoselective C-radical addition to a chiral glyoxylate-derived N-sulfinyl
imine was developed through visible light-promoted photoredox catalysis, providing a …

The incorporation of noncanonical amino acids into proteins and protein-based materials
has significantly expanded the repertoire of available protein structures and chemistries …