Molecular genetics of mycobacteriophages

GF Hatfull - Molecular genetics of mycobacteria, 2014 - Wiley Online Library
Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium
smegmatis and Mycobacterium tuberculosis. The first mycobacteriophages were isolated in …

Mycobacteriophages as potential therapeutic agents against drug-resistant tuberculosis

A Allué-Guardia, R Saranathan, J Chan… - International journal of …, 2021 - mdpi.com
The current emergence of multi-, extensively-, extremely-, and total-drug resistant strains of
Mycobacterium tuberculosis poses a major health, social, and economic threat, and stresses …

[图书][B] Molecular genetics of mycobacteria

GF Hatfull, WR Jacobs Jr - 2020 - books.google.com
A comprehensive collection of perspectives by experts in mycobacterial molecular biology
Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world …

Emerging markers for antimicrobial resistance monitoring

Z Yi, X Xu, X Meng, C Liu, Q Zhou, D Gong… - Chinese Chemical …, 2023 - Elsevier
The appearance and spread of antibiotic-resistant pathogens known as antimicrobial
resistance (AMR) is one of the major worldwide health crises that humanity have to deal with …

Phage-based detection of bacterial pathogens

RG Van der Merwe, PD Van Helden, RM Warren… - Analyst, 2014 - pubs.rsc.org
Bacterial pathogens cause significant morbidity and mortality annually to both humans and
animals. With the rampant spread of drug resistance and the diminishing effectiveness of …

Development of a novel bacteriophage based biomagnetic separation method as an aid for sensitive detection of viable Escherichia coli

Z Wang, D Wang, J Chen, DA Sela, SR Nugen - Analyst, 2016 - pubs.rsc.org
The application of bacteriophage combined with the use of magnetic separation techniques
has emerged as a valuable tool for the sensitive identification and detection of bacteria. In …

Genetic manipulation of phages for therapy using BRED

F Payaslian, V Gradaschi, M Piuri - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Phage therapy is emerging as an alternative to antibiotics.•The first case of phage
therapy in humans using engineered phages is discussed.•This was also the first case of …

Application of bacteriophage in rapid detection of Escherichia coli in foods

J Wang, A Kanach, R Han, B Applegate - Current Opinion in Food Science, 2021 - Elsevier
Food is a common vehicle for introducing Escherichia coli into humans which can result in
serious disease. Efficient and rapid detection of E. coli in the multitude of food and beverage …

Genetics and genomics of bacteriophages: The evolution of bacteriophage genomes and genomic research

A Casey, A Coffey, O McAuliffe - Bacteriophages: Biology, Technology …, 2021 - Springer
In recent years, advancements in sequencing technology and genome analysis software
have broadened the horizons for bacteriophage research. As the repository of data …

Genetic manipulation of lytic bacteriophages with BRED: bacteriophage recombineering of electroporated DNA

LJ Marinelli, M Piuri, GF Hatfull - Bacteriophages: Methods and Protocols …, 2019 - Springer
We describe a recombineering-based method for the genetic manipulation of lytically
replicating bacteriophages, focusing on mycobacteriophages. The approach utilizes …