Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …

In vivo imaging is an important tool for preclinical studies of lung function and disease. The
widespread availability of multimodal animal imaging systems and the rapid rate of …

Background The intratracheal instillation of bleomycin in mice induces early damage to
alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes …

Implementation of in vivo high-resolution micro-computed tomography (µCT), a powerful tool
for longitudinal analysis of murine lung disease models, is hampered by the lack of data on …

In spite of many compounds identified as antifibrotic in preclinical studies, pulmonary fibrosis
remains a life-threatening condition for which highly effective treatment is still lacking …

Background Excessive eosinophil airway infiltration is a clinically critical condition in some
cases. Eosinophilic pneumonia (EP) is a pulmonary condition involving eosinophil …

Background Purinergic receptors control cell proliferation, apoptosis, migration,
inflammation, and cytokine secretion. Increased expression of specific purinergic receptors …

Ethnopharmacological relevance PM014 is a modified form of the Chung-Sang-Bo-Ha-Tang
(CSBHT) herbal formula that has been used to treat chronic pulmonary diseases in Korea for …

Asthma is characterized by airway inflammatory infiltration, which leads to airway
remodeling and airway hyperreactivity. Coleus forskohlii (CFK) has been used to treat …

Asthma is a chronic disease characterized by bronchial hyperresponsiveness (BHR),
bronchial inflammation and remodeling. The great improvements in 1H MRI ultrashort‐TE …