The critical importance of the immunoregulatory mechanisms, which prevent adverse
responses to dietary proteins is demonstrated by the consequences of their failure in two …

Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Recent
studies have revealed that interactions between pathogenic microorganisms, which have a …

Elevated immunoglobulin E (IgE) is a hallmark of allergic diseases. However, high IgE levels
also occur in a number of other infectious and noninfectious diseases. In most cases …

Purpose Major histocompatibility complex class II (MHC-II) deficiency is a rare inborn error of
immunity (IEI). Impaired antigen presentation to CD4+ T cells results in combined …

(1) Background: Atopic dermatitis constitutes one of the most common inflammatory skin
manifestations of the pediatric population. The onset of many inborn errors occurs early in …

Heterozygous variants in the Poly (U) Binding Splicing Factor 60kDa gene (PUF60) have
been associated with Verheij syndrome, which has the key features of coloboma, short …

Background Major histocompatibility complex class II deficiency, a combined
immunodeficiency, results from loss of HLA class II expression on antigen-presenting cells …

The genome of Trypanosoma cruzi was first made available in 2005, and the intrinsic
genome complexity of this parasite has hindered high-quality genome assembly and …

Background There are now approximately 450 discrete inborn errors of immunity (IEI)
described; however, diagnostic rates remain suboptimal. Use of structured health record …

喘息是一种儿童常见的易反复发作的呼吸系统疾病, 发生率高, 病情急重, 住院频繁.
目前越来越多的证据表明喘息发作的儿童大部分存在着超重/肥胖的情况, 这可能与喘息的发作 …