Derivation of male germ cells from induced pluripotent stem cells by inducers: A review

JA Mahabadi, H Sabzalipoor, M Kehtari, SE Enderami… - Cytotherapy, 2018 - Elsevier
Induced pluripotent stem cells (iPSCs) refer to stem cells that are artificially produced using
a new technology known as cellular reprogramming, which can use gene transduction in …

Comparing the adult and pre‐pubertal testis: Metabolic transitions and the change in the spermatogonial stem cell metabolic microenvironment

AL Voigt, N de Lima e Martins Lara, I Dobrinski - Andrology, 2023 - Wiley Online Library
Background Survivors of childhood cancer often suffer from infertility. While sperm
cryopreservation is not feasible before puberty, the patient's own spermatogonial stem cells …

Metabolic transitions define spermatogonial stem cell maturation

AL Voigt, R Dardari, L Su, NLM Lara… - Human …, 2022 - academic.oup.com
STUDY QUESTION Do spermatogonia, including spermatogonial stem cells (SSCs),
undergo metabolic changes during prepubertal development? SUMMARY ANSWER Here …

[HTML][HTML] Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli …

B Niu, B Li, C Wu, J Wu, Y Yan, R Shang, C Bai, G Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Melatonin has been reported to be an important endogenous hormone for regulating
neurogenesis, immunityand the biological clock. Recently, the effects of melatonin on neural …

Effects of Growth Factors on In Vitro Culture of Neonatal Piglet Testicular Tissue Fragments

F Ibtisham, TC Cham, MA Fayaz, A Honaramooz - Cells, 2023 - mdpi.com
In vitro spermatogenesis (IVS) has important applications including fertility preservation of
prepubertal cancer patients; however, thus far, IVS has only been achieved using mouse …

EGF, GDNF, and IGF-1 influence the proliferation and stemness of ovine spermatogonial stem cells in vitro

BK Binsila, S Selvaraju, SK Ghosh, L Ramya… - Journal of Assisted …, 2020 - Springer
Purpose The objective of the present study was to purify sheep spermatogonial stem cells
(SSCs) from testicular isolate using combined enrichment methods and to study the effect of …

Isolation and Culture of Pig Spermatogonial Stem Cells and Their in Vitro Differentiation into Neuron-Like Cells and Adipocytes

X Wang, T Chen, Y Zhang, B Li, Q Xu… - International journal of …, 2015 - mdpi.com
Spermatogonial stem cells (SSCs) renew themselves throughout the life of an organism and
also differentiate into sperm in the adult. They are multipopent and therefore, can be induced …

Molecular characteristics and regulatory role of insulin-like growth factor 1 gene in testicular Leydig cells of Tibetan sheep

Y Wu, Q Li, X Qi, Z Liu, C Wang, X Zhao, Y Ma - Scientific Reports, 2024 - nature.com
This study aimed to analyze the molecular characteristics of insulin-like growth factor 1
(IGF1) gene in the testes of Tibetan sheep and its role in the testosterone synthesis and cell …

Propagation of goat putative spermatogonial stem cells under growth factors defined serum-free culture conditions

A Sharma, SM Shah, M Tiwari, M Roshan, MK Singh… - Cytotechnology, 2020 - Springer
In the present study, we used a serum-free culture media to propagate goat putative
spermatogonial stem cells (SSCs) and evaluated the effect of crucial growth factors on …

Gene expression dynamics during the gonocyte to spermatogonia transition and spermatogenesis in the domestic yak

G Wang, Y Li, Q Yang, S Xu, S Ma, R Yan… - Journal of Animal …, 2019 - Springer
Background Spermatogenesis is a cellular differentiation process that includes three major
events: mitosis of spermatogonia, meiosis of spermatocytes and spermiogenesis. Steady …