Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro

B Prasad, D Grimm, SM Strauch, GS Erzinger… - International journal of …, 2020 - mdpi.com
All life forms have evolved under the constant force of gravity on Earth and developed ways
to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …

Oxidative stress in diseases of the human cornea

A Shoham, M Hadziahmetovic, JL Dunaief… - Free Radical Biology …, 2008 - Elsevier
Intense exposure to light, robust metabolic activity, and high oxygen tension render the
human eye particularly vulnerable to oxidative damage and the list of ophthalmological …

Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property

L Papucci, N Schiavone, E Witort, M Donnini… - Journal of Biological …, 2003 - ASBMB
The permeability transition pore (PTP) is a mitochondrial channel whose opening causes
the mitochondrial membrane potential (ΔΨ) collapse that leads to apoptosis. Some …

Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes

C Gambato, A Ghirlando, E Moretto, F Busato… - Ophthalmology, 2005 - Elsevier
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH)
after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double …

Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage

M Lulli, E Witort, L Papucci, E Torre… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: To evaluate if coenzyme Q10 (CoQ10) can protect retinal ganglion cells (RGCs)
from apoptosis and, when instilled as eye drops on the cornea, if it can reach the retina and …

The role of citicoline and coenzyme Q10 in retinal pathology

C García-López, V García-López… - International Journal of …, 2023 - mdpi.com
Ocular neurodegenerative diseases such as glaucoma, diabetic retinopathy, and age-
related macular degeneration are common retinal diseases responsible for most of the …

Corneal haze post photorefractive keratectomy

S Charpentier, C Keilani, M Maréchal, C Friang… - Journal Français d' …, 2021 - Elsevier
Corneal haze represents subepithelial corneal fibrosis, a manifestation of a pathological
healing process. It occurs as a result of an epithelial-stromal lesion involving a break in the …

Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury

EY Zernii, OS Gancharova, VV Tiulina… - BMC …, 2018 - Springer
Background Cornea protects the eye against natural and anthropogenic ultraviolet (UV)
damage and mechanical injury. Corneal incisions produced by UV lasers in ophthalmic …

[HTML][HTML] Hsp70 expression induced by Co-Enzyme Q10 protected chicken myocardial cells from damage and apoptosis under in vitro heat stress

J Xu, S Tang, E Song, B Yin, D Wu, E Bao - Poultry Science, 2017 - Elsevier
The aim of this study was to investigate whether induction of Hsp70 expression by co-
enzyme Q10 (Q10) treatment protects chicken primary myocardial cells (CPMCs) from …

Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo

M Lulli, E Witort, L Papucci, E Torre… - Journal of radiation …, 2012 - academic.oup.com
The key pathogenetic event of many retinopathies is apoptosis of retinal cells. Our previous
studies have demonstrated that Coenzyme Q10 (CoQ10) prevents apoptosis of corneal …