SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

F Bertoglio, V Fühner, M Ruschig, PA Heine, L Abassi… - Cell reports, 2021 - cell.com
The novel betacoronavirus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)
causes a form of severe pneumonia disease called coronavirus disease 2019 (COVID-19) …

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients by phage display is binding to the ACE2-RBD interface and is tolerant to most known recently …

F Bertoglio, V Fühner, M Ruschig, PA Heine, L Abasi… - BioRxiv, 2020 - biorxiv.org
The novel betacoranavirus SARS-CoV-2 causes a form of severe pneumonia disease,
termed COVID-19 (coronavirus disease 2019). Recombinant human antibodies are proven …

An inclusive study of deleterious missense PAX9 variants using user-friendly tools reveals structural, functional alterations, as well as potential therapeutic targets.

P Ranjan, P Das - International Journal of Biological Macromolecules, 2023 - Elsevier
Mutations in the PAX9 are responsible for non-syndromic tooth agenesis in humans,
although their structural and functional consequences on protein phenotype, stability, and …

The influence of new SARS-CoV-2 variant Omicron (B. 1.1. 529) on vaccine efficacy, its correlation to Delta variants: A computational approach

P Ranjan, C Devi, KA Devar, P Das - Microbial Pathogenesis, 2022 - Elsevier
The newly discovered COVID variant B. 1.1. 529 in Botswana has more than 30 mutations in
spike and many other in non-spike proteins, far more than any other SARS-CoV-2 variant …

Understanding the impact of missense mutations on the structure and function of the EDA gene in X‐linked hypohidrotic ectodermal dysplasia: A bioinformatics …

P Ranjan, P Das - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
X‐linked hypohidrotic dysplasia (XLHED), caused by mutations in the EDA gene, is a rare
genetic disease that affects the development and function of the teeth, hair, nails, and sweat …

Binding affinity improvement analysis of multiple-mutant Omicron on 2019-nCov to human ACE2 by in silico predictions

B Li, J Guo, W Hu, Y Chen - Journal of Molecular Modeling, 2023 - Springer
Context Since the outbreak of COVID-19 in 2019, the 2019-nCov coronavirus has appeared
diverse mutational characteristics due to its own flexible conformation. One multiple-mutant …

An in vitro and computational validation of a novel loss-of-functional mutation in PAX9 associated with non-syndromic tooth agenesis

T Sarkar, P Ranjan, S Kanathur, A Gupta… - Molecular Genetics and …, 2023 - Springer
Congenital tooth agenesis (CTA) is one of the most common craniofacial anomalies. Its
frequency varies among different population depending upon the genetic heterogeneity …

A Data Analytics-Based Study in SARS-CoV-2 Genome Revealed a Commonality in the Infection Pattern

M Dash, VS Kumar, P Meher, ND Namsa - International Conference on …, 2022 - Springer
Severe acute respiratory syndrome (SARS) is an infection caused by the virus SARS-CoV-2,
initially reported in the Wuhan province of China. Due to the rapid infectious and mutational …

Emergence of B. 1.617 Strain of Covid-19 in India and attitude, awareness, perception of dental professionals and its effect on dentistry: A Survey Report

A Sharma - UNIVERSITY JOURNAL OF DENTAL SCIENCES, 2021 - ujds.in
Objective-To know the attitude, awareness and perception of dental practitioners about
double mutant virus in India and how it is affecting their practice. Material & Method-The …