In adult mammals, the subventricular zone (SVZ) of the lateral ventricles and the
subgranular zone of the dentate gyrus (DG) show ongoing neurogenesis, and multipotent …

A new paradigm for drug research has emerged, namely the deliberate search for molecules
able to selectively affect the proliferation, differentiation, and migration of adult stem cells …

Neural stem cells (NSCs) are important pluripotent stem cells, which have potential
applications in cell replacement therapy. Brain-derived neurotrophic factor (BDNF) and …

Spinal cord injury (SCI) remains a devastating condition with poor prognosis and very
limited treatment options. Affected patients are severely restricted in their daily activities …

The presence of 5-methylcytosine (m5C) in RNA molecules has been known for decades
and its importance in regulating RNA metabolism has gradually become appreciated …

We developed a silicon nanowire based electrical cell impedance sensor (SiNW-ECIS) as
an instrument that detects cancerous cultured living lung cells by monitoring their spreading …

Although a myriad of pathological responses contribute to traumatic brain injury (TBI),
cerebral dysfunction has been closely linked to cell death mechanisms. A number of …

During neurogenesis, dynamic developmental cues, transcription factors and histone
modifying enzymes regulate the gene expression programs by modulating the activity of …

Background Folate is an essential B-group vitamin and a key methyl donor with important
biological functions including DNA methylation regulation. Normal neurodevelopment and …

Post-transcriptional RNA modifications have been recognized as key regulators of neuronal
differentiation and synapse development in the mammalian brain. While distinct sets of 5 …