Among the central goals of stress neurobiology research is to understand the mechanisms
by which stressors change neural circuit function to precipitate or exacerbate psychiatric …

Fiber photometry enables recording of population neuronal calcium dynamics in awake
mice. While the popularity of fiber photometry has grown in recent years, it remains unclear …

Infections induce a set of pleiotropic responses in animals, including anorexia, adipsia,
lethargy and changes in temperature, collectively termed sickness behaviours. Although …

Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are effective antiobesity
drugs. However, the precise central mechanisms of GLP-1RAs remain elusive. We …

Over the course of mammalian evolution, the ability to store energy likely conferred a
survival advantage when food became scarce. A long‐term increase in energy storage …

Food intake follows a predictable daily pattern and synchronizes metabolic rhythms.
Neurons expressing agouti-related protein (AgRP) read out physiological energetic state …

Feeding behaviors depend on intrinsic and extrinsic factors including genetics, food
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …

Motivated behaviors are often studied in isolation to assess labeled lines of neural
connections underlying innate actions. However, in nature, multiple systems compete for …

How does binge drinking alcohol change synaptic function, and do these changes maintain
binge consumption? The anterior insular cortex (AIC) and dorsolateral striatum (DLS) are …

Psilocybin has shown promise as a novel pharmacological intervention for treatment of
depression, where post-acute effects of psilocybin treatment have been associated with …