Background and Design: The concurrent finding of neurofibromatosis type 1 (NF), juvenile
chronic myelogenous leukemia (JCML), and juvenile xanthogranuloma (JXG) has been …

The molecular bases of brain development and CNS malignancies remain poorly
understood. Here we show that Sonic hedgehog (Shh) signaling controls the development …

Abstract The Birt-Hogg-Dubé syndrome, a genodermatosis characterized by benign tumors
of the hair follicle, has been associated with renal and colonic neoplasms and spontaneous …

Sporadic basal cell carcinoma (BCC) is the most common type of malignant cancer in fair-
skinned adults. Familial BCCs and a fraction of sporadic BCCs have lost the function of …

This book provides an authoritative guide to the histological and genetic typing of human
tumors of the skin. This volume covers keratinocytic, melanocytic, appendageal …

Background: Prophylactic surgical excision of nevus sebaceus (NS) during childhood is
often recommended because various neoplasms can occur on NS. The proportion of …

Bone morphogenetic protein (BMP) signaling is thought to perform multiple functions in the
regulation of skin appendage morphogenesis and the postnatal growth of hair follicles …

Basal cell carcinoma is the most prevalent cancer in the western world, showing a rapid
increase in incidence. Activation of the Sonic hedgehog/Patched (PTCH) signaling pathway …

Background Nevus sebaceus is commonly associated with the development of secondary
neoplasms. Data on the frequency of malignant tumors vary considerably in published …

Quickly and confidently evaluate and diagnose skin biopsies with Practical
Dermatopathology. Written from the perspective of both the histopathologist and clinician …