Living materials, which are made either of or by living cells, or are synthetic materials with
programmable elements catered to cells, are environmentally responsive and can self …

The paper presents a review of models that can be used to describe dynamics of lung
cancer growth and its response to treatment at both cell population and intracellular …

Hepatic stellate cells (HSC) are the source of extracellular matrix (ECM) whose
overproduction leads to fibrosis, a condition that impairs liver functions in chronic liver …

Although infectious disease dynamics are often analyzed at the macroscale, increasing
numbers of drug-resistant infections highlight the importance of within-host modeling that …

Multiscale models provide a unique tool for analyzing complex processes that study events
occurring at different scales across space and time. In the context of biological systems, such …

Investigating the molecular, cellular, and tissue-level changes caused by disease, and the
effects of pharmacological treatments across these biological scales, necessitates the use of …

Diabetic kidney disease is a complication in 1 out of 3 patients with diabetes. Aberrant
glucose metabolism in diabetes leads to an immune response causing inflammation and to …

Diabetes mellitus affects more than 30 million people in the United States and more than
400 million people worldwide. It is estimated that 90-95% of these people have type 2 …

Bone remodeling is an essential, delicately balanced physiological process of coordinated
activity of bone cells that remove and deposit new bone tissue in the adult skeleton. Due to …

Klebsiella pneumoniae (K. pneumoniae) is a pathogen that has been identified as the
leading cause of pneumonia and septicemia worldwide, compounded by its multi-drug …