Stem cell biology has played a pivotal role in the field of disease modeling, regenerative
medicine, and tissue engineering. The scope of stem cell research has been further …

Neurodegeneration and neurodegenerative disorders have been a global health issue
affecting the aging population worldwide. Recent advances in stem cell biology have …

The present study examined the efficacy of a neural induction method for human induced
pluripotent stem (iPS) cells to eliminate undifferentiated cells and to determine the feasibility …

Fluorescence long-term imaging of cellular processes in three-dimensional cultures requires
the control of media supply, temperature, and pH, as well as minimal photodamage. We …

We investigated the design of neurotrophic biomaterial constructs for human neural stem
cells, guided by neural developmental cues of N-cadherin and L1 adhesion molecules …

Pluripotent stem cells (PSCs) offer an excellent model to study neural development and
function. Although various protocols have been developed to direct the differentiation of …

Dinitrophenol (DNP) is a neuroprotective compound previously shown to promote neuronal
differentiation in a neuroblastoma cell line and neurite outgrowth in primary neurons. Here …

Differentiation of pluripotent stem cells, PSCs, towards neural lineages has attracted
significant attention, given the potential use of such cells for in vitro studies and for …

Neural progenitor cells are usually derived from pluripotent stem cells (PSCs) through the
formation of embryoid bodies (EBs), the three-dimensional (3D) aggregate-like structure …

Angelman Syndrome (AS) is an imprinted neurodevelopmental disease with no cure caused
by the lack of UBE3A expression, which, in neurons, is exclusively maternally expressed …