The etiology of preeclampsia

E Jung, R Romero, L Yeo, N Gomez-Lopez… - American journal of …, 2022 - Elsevier
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …

Major coagulation disorders and parameters in COVID-19 patients

A Teimury, MT Khameneh, EM Khaledi - European journal of medical …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), with a high prevalence rate, has rapidly
infected millions of people around the world. Since viral infections can disrupt the …

Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients

JL Zhang, YH Li, LL Wang, HQ Liu, SY Lu… - Signal transduction and …, 2021 - nature.com
Azvudine (FNC) is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase
(RdRp). Recently, we discovered FNC an agent against SARS-CoV-2, and have taken it into …

[HTML][HTML] SARS-CoV-2 infection and multi-organ system damage: A review

AA Rabaan, S Smajlović, H Tombuloglu… - Biomolecules and …, 2023 - ncbi.nlm.nih.gov
The SARS-CoV-2 infection causes COVID-19, which has affected approximately six hundred
million people globally as of 8 2022. Organs and cells harboring angiotensin-converting …

A novel hypothesis for COVID-19 pathogenesis: Retinol depletion and retinoid signaling disorder

AR Sarohan, M Kızıl, AÇ İnkaya, S Mahmud, M Akram… - Cellular signalling, 2021 - Elsevier
The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year
and a half, more than 200 million people have been infected and more than four million …

Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and complement

M Sayyadi, S Hassani, M Shams, A Dorgalaleh - Annals of Hematology, 2023 - Springer
The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …

Red blood cell abnormalities as the mirror of SARS-CoV-2 disease severity: a pilot study

A Bouchla, AG Kriebardis, HT Georgatzakou… - Frontiers in …, 2022 - frontiersin.org
Purpose Unraveling the pathophysiology of COVID-19 disease is of crucial importance for
designing treatment. The purpose of this study is to investigate the effects of the disease on …

Radiation-induced lung injury—current perspectives and management

MS Rahi, J Parekh, P Pednekar, G Parmar… - Clinics and …, 2021 - mdpi.com
Radiotherapy plays an important role in the treatment of localized primary malignancies
involving the chest wall or intrathoracic malignancies. Secondary effects of radiotherapy on …

Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement …

F Ciccosanti, M Antonioli, A Sacchi, S Notari, A Farina… - Clinical proteomics, 2022 - Springer
Most patients infected with SARS-CoV-2 display mild symptoms with good prognosis, while
20% of patients suffer from severe viral pneumonia and up to 5% may require intensive care …

[HTML][HTML] Viral load and patterns of SARS-CoV-2 dissemination to the lungs, mediastinal lymph nodes, and spleen of patients with COVID-19 associated lymphopenia

A Abdullaev, A Odilov, M Ershler, A Volkov, T Lipina… - Viruses, 2021 - mdpi.com
Lymphopenia is a frequent hematological manifestation, associated with a severe course of
COVID-19, with an insufficiently understood pathogenesis. We present molecular genetic …