Evidence for SARS-CoV-2 infection of animal hosts

AS Abdel-Moneim, EM Abdelwhab - Pathogens, 2020 - mdpi.com
COVID-19 is the first known pandemic caused by a coronavirus, SARS-CoV-2, which is the
third virus in the family Coronaviridae to cause fatal infections in humans after SARS-CoV …

The importance of animal models in biomedical research: current insights and applications

A Domínguez-Oliva, I Hernández-Ávalos… - Animals, 2023 - mdpi.com
Simple Summary The present review highlights and examines the importance of animal
models in relevant topics concerning current human and animal health. Over the past five …

[HTML][HTML] The technology, opportunities and challenges of synthetic biological intelligence

BJ Kagan, C Gyngell, T Lysaght, VM Cole… - Biotechnology …, 2023 - Elsevier
Integrating neural cultures developed through synthetic biology methods with digital
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …

The sheep as a large animal model for the investigation and treatment of human disorders

A Banstola, JNJ Reynolds - Biology, 2022 - mdpi.com
Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

[HTML][HTML] Implications of genetic variation in the complement system in age-related macular degeneration

S de Jong, G Gagliardi, A Garanto, A de Breuk… - Progress in Retinal and …, 2021 - Elsevier
Age-related macular degeneration (AMD) is the main cause of vision loss among the elderly
in the Western world. While AMD is a multifactorial disease, the complement system was …

Post-translational regulations of Foxp3 in Treg cells and their therapeutic applications

Y Dong, C Yang, F Pan - Frontiers in Immunology, 2021 - frontiersin.org
Regulatory T (Treg) cells are indispensable for immune homeostasis due to their roles in
peripheral tolerance. As the master transcription factor of Treg cells, Forkhead box P3 …

Lassa fever research priorities: towards effective medical countermeasures by the end of the decade

KA Moore, JT Ostrowsky, AJ Mehr… - The Lancet Infectious …, 2024 - thelancet.com
In 2016, WHO designated Lassa fever a priority disease for epidemic preparedness as part
of the WHO Blueprint for Action to Prevent Epidemics. One aspect of preparedness is to …

Global wildlife trade and trafficking contribute to the world's nonhuman primate conservation crisis

PA Garber, A Estrada, S Shanee… - Frontiers in …, 2024 - frontiersin.org
A growing global human population, habitat conversion, and the indiscriminate exploitation
of natural resources have created unsustainable demands on nature, resulting in …

[HTML][HTML] International primate neuroscience research regulation, public engagement and transparency opportunities

AS Mitchell, R Hartig, MA Basso, W Jarrett, S Kastner… - Neuroimage, 2021 - Elsevier
Scientific excellence is a necessity for progress in biomedical research. As research
becomes ever more international, establishing international collaborations will be key to …

Large animal models of glioma: Current status and future prospects

WH Hicks, CE Bird, MN Pernik, AS Haider… - Anticancer …, 2021 - ar.iiarjournals.org
Enhanced understanding of the molecular features of glioma has led to an expansion of
murine glioma models and successful preclinical studies. However, clinical trials continue to …