Neuromodulation of Innate Behaviors in Drosophila

SM Kim, CY Su, JW Wang - Annual review of neuroscience, 2017 - annualreviews.org
Animals are born with a rich repertoire of robust behaviors that are critical for their survival.
However, innate behaviors are also highly adaptable to an animal's internal state and …

[HTML][HTML] Lessons from lonely flies: Molecular and neuronal mechanisms underlying social isolation

RSP Yadav, F Ansari, N Bera, C Kent… - … & Biobehavioral Reviews, 2024 - Elsevier
Animals respond to changes in the environment which affect their internal state by adapting
their behaviors. Social isolation is a form of passive environmental stressor that alters …

Chemoconnectomics: mapping chemical transmission in Drosophila

B Deng, Q Li, X Liu, Y Cao, B Li, Y Qian, R Xu, R Mao… - Neuron, 2019 - cell.com
We define the chemoconnectome (CCT) as the entire set of neurotransmitters,
neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an …

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

VK Gupta, L Scheunemann, T Eisenberg, S Mertel… - Nature …, 2013 - nature.com
Age-dependent memory impairment is known to occur in several organisms, including
Drosophila, mouse and human. However, the fundamental cellular mechanisms that …

An octopamine receptor confers selective toxicity of amitraz on honeybees and Varroa mites

L Guo, X Fan, X Qiao, C Montell, J Huang - Elife, 2021 - elifesciences.org
The Varroa destructor mite is a devastating parasite of Apis mellifera honeybees. They can
cause colonies to collapse by spreading viruses and feeding on the fat reserves of adults …

The Neurotransmitters Involved in Drosophila Alcohol-Induced Behaviors

MM Chvilicek, I Titos, A Rothenfluh - Frontiers in behavioral …, 2020 - frontiersin.org
Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …

She's got nerve: roles of octopamine in insect female reproduction

MA White, DS Chen, MF Wolfner - Journal of neurogenetics, 2021 - Taylor & Francis
The biogenic monoamine octopamine (OA) is a crucial regulator of invertebrate physiology
and behavior. Since its discovery in the 1950s in octopus salivary glands, OA has been …

Regulation of sleep homeostasis by sexual arousal

EJ Beckwith, Q Geissmann, AS French, GF Gilestro - Elife, 2017 - elifesciences.org
In all animals, sleep pressure is under continuous tight regulation. It is universally accepted
that this regulation arises from a two-process model, integrating both a circadian and a …

Drosophila Insulin-Producing Cells Are Differentially Modulated by Serotonin and Octopamine Receptors and Affect Social Behavior

J Luo, OV Lushchak, P Goergen, MJ Williams… - PloS one, 2014 - journals.plos.org
A set of 14 insulin-producing cells (IPCs) in the Drosophila brain produces three insulin-like
peptides (DILP2, 3 and 5). Activity in IPCs and release of DILPs is nutrient dependent and …

The Octopamine Receptor Octβ2R Regulates Ovulation in Drosophila melanogaster

J Lim, PR Sabandal, A Fernandez, JM Sabandal… - PloS one, 2014 - journals.plos.org
Oviposition is induced upon mating in most insects. Ovulation is a primary step in
oviposition, representing an important target to control insect pests and vectors, but limited …