Analytical methods for characterization of nanomaterial surfaces

HSN Jayawardena, SH Liyanage… - Analytical …, 2021 - ACS Publications
The physicochemical parameters of nanomaterials, includ-ing the size, shape, core
structure, and surface ligands, govern the properties as well as the utilities of nanomaterials …

Engineering at the nano-bio interface: harnessing the protein corona towards nanoparticle design and function

RL Pinals, L Chio, F Ledesma, MP Landry - Analyst, 2020 - pubs.rsc.org
Unpredictable and uncontrollable protein adsorption on nanoparticles remains a
considerable challenge to achieving effective application of nanotechnologies within …

The use of medicinal plant-derived metallic nanoparticles in theranostics

JH Xulu, T Ndongwe, KM Ezealisiji, VJ Tembu… - Pharmaceutics, 2022 - mdpi.com
In the quest to effectively diagnose and treat the diseases that afflict mankind, the
development of a tool capable of simultaneous detection and treatment would provide a …

Biological effects of formation of protein corona onto nanoparticles

RK Mishra, A Ahmad, A Vyawahare, P Alam… - International journal of …, 2021 - Elsevier
Administration of nanomaterials based medicinal and drug carrier systems into systemic
circulation brings about interaction of blood components eg albumin and globulin proteins …

Understanding the adsorption of peptides and proteins onto PEGylated gold nanoparticles

YR Perera, JX Xu, DL Amarasekara, AC Hughes… - Molecules, 2021 - mdpi.com
Polyethylene glycol (PEG) surface conjugations are widely employed to render passivating
properties to nanoparticles in biological applications. The benefits of surface passivation by …

Biomolecular interactions of ultrasmall metallic nanoparticles and nanoclusters

AA Sousa, P Schuck, SA Hassan - Nanoscale Advances, 2021 - pubs.rsc.org
The use of nanoparticles (NPs) in biomedicine has made a gradual transition from proof-of-
concept to clinical applications, with several NP types meeting regulatory approval or …

Quantitative measurement of multiprotein nanoparticle interactions using NMR spectroscopy

JX Xu, MS Alom, NC Fitzkee - Analytical chemistry, 2021 - ACS Publications
An effective intensity-based reference is a cornerstone for quantitative nuclear magnetic
resonance (NMR) studies, as the molecular concentration is encoded in its signal. In theory …

Predicting protein function and orientation on a gold nanoparticle surface using a residue-based affinity scale

JX Xu, MS Alom, R Yadav, NC Fitzkee - Nature Communications, 2022 - nature.com
The orientation adopted by proteins on nanoparticle surfaces determines the nanoparticle's
bioactivity and its interactions with living systems. Here, we present a residue-based affinity …

Solution NMR methods for structural and thermodynamic investigation of nanoparticle adsorption equilibria

Y An, SL Sedinkin, V Venditti - Nanoscale Advances, 2022 - pubs.rsc.org
Characterization of dynamic processes occurring at the nanoparticle (NP) surface is crucial
for developing new and more efficient NP catalysts and materials. Thus, a vast amount of …

New Paradigm for Nano–Bio Interactions: Multimolecular Assembly of a Prototypical Disordered Protein with Ultrasmall Nanoparticles

G Viola, CG Barracchia, R Tira, F Parolini, G Leo… - Nano Letters, 2022 - ACS Publications
Understanding the interactions between nanoparticles (NPs) and proteins is crucial for the
successful application of NPs in biological contexts. Protein adsorption is dependent on …