Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive
and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification. In turn …

Abstract Introduction Hepatitis C virus (HCV) is a major public health threat. Although the
recent availability of highly effective directly acting antivirals created optimism towards HCV …

The recommendations in this report supersede the US Public Health Service (PHS)
guideline recommendations for reducing transmission of human immunodeficiency virus …

Background: Drug repurposing is the fastest effective method to provide treatment for
coronavirus disease (COVID-19). Drugs that targeting a closely related virus with similar …

Abstract The Infectious Diseases Society of America and the American Association for the
Study of Liver Diseases have collaboratively developed evidence-based guidance …

Background Direct-acting antiviral (DAA) therapy enables a high rate of sustained virologic
response (SVR) in patients with hepatitis C virus associated cirrhosis. However, the impact …

Drug‐drug interaction (DDI) is a common clinical problem that has occurred as a result of the
concomitant use of multiple drugs. DDI may occur in patients under treatment with …

Whereas 16S rRNA gene amplicon sequencing quantifies relative abundances of bacterial
taxa, variation in total bacterial load between samples restricts its ability to reflect absolute …

Background Real-world data on the efficacy and safety of sofosbuvir plus velpatasvir
(SOF/VEL) treatment for patients with hepatitis C virus (HCV)-related decompensated …