Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …

Knowledge of the inherited risk for cancer is an important component of preventive
oncology. In addition to well-established syndromes of cancer predisposition, much remains …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

We report a prostate cancer genome-wide association follow-on study. We discovered four
variants associated with susceptibility to prostate cancer in several European populations …

Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics,
but the causal links between increased genetic risk and onset/progression of disease …

Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in
developed countries and the second leading cause of cancer mortality, yet little is known …

Most men diagnosed with prostate cancer will experience indolent disease; hence,
discovering genetic variants that distinguish aggressive from nonaggressive prostate cancer …

A genome-wide association study (GWAS) of prostate cancer in Kaiser Permanente health
plan members (7,783 cases, 38,595 controls; 80.3% non-Hispanic white, 4.9% African …

Long non-coding RNAs (lncRNAs), representing a large proportion of non-coding transcripts
across the human genome, are evolutionally conserved and biologically functional. At least …

BACKGROUND: More than 1 million prostate biopsies are conducted yearly in the United
States. The low specificity of prostate-specific antigen (PSA) results in diagnostic biopsies in …