The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders

E Knezevic, K Nenic, V Milanovic, NN Knezevic - Cells, 2023 - mdpi.com
Cortisol, a critical glucocorticoid hormone produced by the adrenal glands, plays a pivotal
role in various physiological processes. Its release is finely orchestrated by the …

Biomarkers for depression: recent insights, current challenges and future prospects

R Strawbridge, AH Young, AJ Cleare - … disease and treatment, 2017 - Taylor & Francis
A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …

Hair cortisol concentrations in mental disorders: a systematic review

EK Malisiova, I Mourikis, C Darviri, NC Nicolaides… - Physiology & …, 2021 - Elsevier
Objective Research on HPA axis dysregulation has been associated with vulnerability to, or
perseverence of, several mental disorders. Hoever, measurements of cortisol levels in …

Associations between chronic stress and hair cortisol in children: A systematic review and meta-analysis

Y Li, W Jia, N Yan, Y Hua, T Han, J Yang, L Ma… - Journal of Affective …, 2023 - Elsevier
Objectives This review systematically examined the associations between chronic stress
and hair cortisol concentration (HCC) in children, and the potential modification effects of …

Heterogeneity in major depressive disorder: the need for biomarker-based personalized treatments

S Suseelan, G Pinna - Advances in Clinical Chemistry, 2023 - Elsevier
Abstract Major Depressive Disorder (MDD) or depression is a pathological mental condition
affecting millions of people worldwide. Identification of objective biological markers of …

Sports drug testing using complementary matrices: advantages and limitations

M Thevis, H Geyer, L Tretzel, W Schänzer - Journal of pharmaceutical and …, 2016 - Elsevier
Today, routine doping controls largely rely on testing whole blood, serum, and urine
samples. These matrices allow comprehensively covering inorganic as well as low and high …

Is there a relation between major depression and hair cortisol? A systematic review and meta-analysis

EE Psarraki, I Kokka, F Bacopoulou… - …, 2021 - Elsevier
Literature supports a causal role of stress in major depressive disorder (MDD). Hair cortisol
concentration (HCC) has been widely used as a measure of long-term stress. Although …

Innovations in biological assessments of chronic stress through hair and nail cortisol: Conceptual, developmental, and methodological issues

CH Liu, SN Doan - Developmental psychobiology, 2019 - Wiley Online Library
Much of the existing research on biological mechanisms underlying the stress experience
has focused largely on moment‐to‐moment stress, rather than on chronic stress, an …

A systematic review of studies utilizing hair glucocorticoids as a measure of stress suggests the marker is more appropriate for quantifying short-term stressors

O Kalliokoski, FK Jellestad, R Murison - Scientific Reports, 2019 - nature.com
Quantitating glucocorticoids (GCs) in hairs is a popular method for assessing chronic stress
in studies of humans and animals alike. The cause-and-effect relationship between stress …

Hypothalamic corticotrophin releasing hormone neurons in stress‐induced psychopathology: Revaluation of synaptic contributions

LM Stanton, AJ Price… - Journal of …, 2023 - Wiley Online Library
Stress has a strong influence on mental health around the world. Decades of research has
sought to identify mechanisms through which stress contributes to psychiatric disorders such …