[HTML][HTML] Recent synthetic efforts towards high energy density materials: How to design high-performance energetic structures?

J Zhou, J Zhang, B Wang, L Qiu, R Xu, AB Sheremetev - FirePhysChem, 2022 - Elsevier
Energetic material is a very essential company of compounds, widely used in various fields,
primarily in the military industry and space technologies. These compounds are unique in …

Applications of bioisosteres in the design of biologically active compounds

NA Meanwell - Journal of Agricultural and Food Chemistry, 2023 - ACS Publications
The design of bioisosteres represents a creative and productive approach to improve a
molecule, including by enhancing potency, addressing pharmacokinetic challenges …

Silver (i)-catalyzed synthesis of cuneanes from cubanes and their investigation as isosteres

E Smith, KD Jones, L O'Brien, SP Argent… - Journal of the …, 2023 - ACS Publications
Bridged or caged polycyclic hydrocarbons have rigid structures that project substituents into
precise regions of 3D space, making them attractive as linking groups in materials science …

Emerging building blocks for medicinal chemistry: recent synthetic advances

OO Grygorenko, DM Volochnyuk… - European Journal of …, 2021 - Wiley Online Library
Current medicinal chemistry relies heavily on the quality of building blocks, ie reagents used
to introduce chemical diversity into the target molecules. The last decade witnessed an …

Bridge functionalisation of bicyclo [1.1. 1] pentane derivatives

JM Anderson, ND Measom, JA Murphy… - Angewandte …, 2021 - Wiley Online Library
Abstract “Escaping from flatland”, by increasing the saturation level and three‐
dimensionality of drug‐like compounds, can enhance their potency, selectivity and …

Nickel-catalyzed decarboxylative cross-coupling of bicyclo [1.1. 1] pentyl radicals enabled by electron donor–acceptor complex photoactivation

VC Polites, SO Badir, S Keess, A Jolit… - Organic letters, 2021 - ACS Publications
The use of bicyclo [1.1. 1] pentanes (BCPs) as para-disubstituted aryl bioisosteres has
gained considerable momentum in drug development programs. Carbon–carbon bond …

Photoinduced strategies towards strained molecules

MMD Pramanik, H Qian, WJ Xiao… - Organic Chemistry …, 2020 - pubs.rsc.org
New photoinduced strategies towards radical reactions of strained molecules such as [1.1.
1] propellane and bicyclo [1.1. 0] butanes by photoredox or metallaphotoredox catalysis …

[PDF][PDF] Comprehensive Investigation of the Potential of Hydrazine and its Derivatives for the Synthesis of Various Molecules with Biological Activity

MM Barqi, A Ashar, ZA Bhutta, M Javed… - chemistry and …, 2023 - researchgate.net
This review paper provides a comprehensive and in-depth analysis of the versatile utility of
hydrazine as a precursor for the synthesis of several significant hydrazides and related …

Recent metal-catalyzed methods for thioether synthesis

VJ Geiger, RM Oechsner, PH Gehrtz, I Fleischer - Synthesis, 2022 - thieme-connect.com
This review summarizes the more recent methods (since 2015) for the synthesis of
thioethers using homogeneous metals as catalysts. The thioether moiety can be found in …

Decoration on Cubane with an Awareness of Chirality: Development of Substituted Cubane Syntheses

H Takebe, S Matsubara - Synthesis, 2024 - thieme-connect.com
Nearly 60 years have passed since Professor Eaton's practical synthesis of cubane, and
research using it as a unique molecular scaffold has since gained momentum. Since the …