Selecting potential targetable biomarkers for imaging purposes in colorectal cancer using TArget Selection Criteria (TASC): a novel target identification tool

M van Oosten, LMA Crane, J Bart… - Translational …, 2011 - Elsevier
Peritoneal carcinomatosis (PC) of colorectal origin is associated with a poor prognosis.
However, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy …

COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer

YH Wu, TH Chang, YF Huang, HD Huang, CY Chou - Oncogene, 2014 - nature.com
Biomarkers that predict disease progression might assist the development of better
therapeutic strategies for aggressive cancers, such as ovarian cancer. Here, we investigated …

Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression

AC Vargas, AEMC Reed, N Waddell, A Lane… - Breast cancer research …, 2012 - Springer
The progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) marks
a critical step in the evolution of breast cancer. There is some evidence to suggest that …

Autophagy in cutaneous malignant melanoma

R Lazova, V Klump, J Pawelek - Journal of cutaneous …, 2010 - Wiley Online Library
We show that malignant melanoma cells display high levels of autophagy, a cytoplasmic
process of protein and organelle digestion that provides an energy source in times of …

Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer

C García-Pravia, JA Galván, N Gutiérrez-Corral… - PloS one, 2013 - journals.plos.org
Background The collagen11A1 (COL11A1) gene is overexpressed in pancreatic cancer.
The expression of COL11A1 protein could be involved in desmoplastic events in pancreatic …

[HTML][HTML] The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through …

H Wang, R Ren, Z Yang, J Cai, S Du, X Shen - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Collagen XI, a member of the collagen family, is present in the extracellular matrix (ECM),
and high collagen XI/αI (COL11A1) expression in tumor tissue is reportedly correlated with …

Integrated bioinformatics analysis of key genes involved in progress of colon cancer

H Yang, J Wu, J Zhang, Z Yang, W Jin… - Molecular genetics & …, 2019 - Wiley Online Library
Background Colon cancer is one of most malignant cancers around worldwide. Nearly 20%
patients were diagnosed at colon cancer with metastasis. However, the lack of …

Collagen, type XI, alpha 1: an accurate marker for differential diagnosis of breast carcinoma invasiveness in core needle biopsies

J Freire, S Domínguez-Hormaetxe, S Pereda… - … -Research and Practice, 2014 - Elsevier
Accurate diagnosis of invasive breast lesions, when analyzed by Core Needle Biopsy, may
suppose a major challenge for the pathologist. Various markers of invasiveness such as …

Validation of COL11A1/procollagen 11A1 expression in TGF-β1-activated immortalised human mesenchymal cells and in stromal cells of human colon …

JA Galván, J García-Martínez, F Vázquez-Villa… - BMC cancer, 2014 - Springer
Abstract Background The human COL11A1 gene has been shown to be up-regulated in
stromal cells of colorectal tumours, but, so far, the immunodetection of procollagen 11A1, the …

A current viewpoint on structure and evolution of collagens. I. Fibrillar collagens

VP Ivanova, AI Krivchenko - Journal of evolutionary biochemistry and …, 2012 - Springer
This review summarizes current data of structure of the most representative group of
superfamily of collagens—fibrillar collagens. The attention is focused on structural …