Type 2 diabetes mellitus in older adults: clinical considerations and management

S Bellary, I Kyrou, JE Brown, CJ Bailey - Nature Reviews Endocrinology, 2021 - nature.com
The past 50 years have seen a growing ageing population with an increasing prevalence of
type 2 diabetes mellitus (T2DM); now, nearly half of all individuals with diabetes mellitus are …

Risk of progression to diabetes among older adults with prediabetes

MR Rooney, AM Rawlings, JS Pankow… - JAMA internal …, 2021 - jamanetwork.com
Importance The termprediabetesis used to identify individuals at increased risk for diabetes.
However, the natural history of prediabetes in older age is not well characterized. Objectives …

Historical review of the diagnosis of prediabetes/intermediate hyperglycemia: case for the international criteria

MB Davidson - Diabetes research and clinical practice, 2022 - Elsevier
In 1997, the ADA recommended an IFG criterion for diagnosing prediabetes/intermediate
hyperglycemia of FPG concentrations of 6.1–6.9 mmol/L (110–125 mg/dL). In 2003, they …

Muscle strength and prediabetes progression and regression in middle‐aged and older adults: a prospective cohort study

S Qiu, X Cai, Y Yuan, B Xie, Z Sun… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Prediabetes progression is associated with increased mortality while its
regression decreases it. It is unclear whether muscle strength is related to prediabetes …

Metformin should not be used to treat prediabetes

MB Davidson - Diabetes Care, 2020 - Am Diabetes Assoc
Based on the results of the Diabetes Prevention Program Outcomes Study (DPPOS), in
which metformin significantly decreased the development of diabetes in individuals with …

Association of fasting glucose with lifetime risk of incident heart failure: the Lifetime Risk Pooling Project

A Sinha, H Ning, FS Ahmad, MP Bancks… - Cardiovascular …, 2021 - Springer
Background Given the rising prevalence of dysglycemia and disparities in heart failure (HF)
burden, we determined race-and sex-specific lifetime risk of HF across the spectrum of …

Association of diabetes with stroke and post‐stroke dementia: a population‐based cohort study

Y Shang, L Fratiglioni, A Marseglia… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction The impact of prediabetes and diabetes on stroke and the development of
dementia after a stroke remain unclear. Methods A total of 2655 dementia‐free participants …

Lifetime risk to progress from pre-diabetes to type 2 diabetes among women and men: comparison between American Diabetes Association and World Health …

TTW van Herpt, S Ligthart, MJG Leening… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction Pre-diabetes, a status conferring high risk of overt diabetes, is defined differently
by the American Diabetes Association (ADA) and the WHO. We investigated the impact of …

Are the determinants of the progression to type 2 diabetes and regression to normoglycemia in the populations with pre-diabetes the same?

Z Alizadeh, HR Baradaran, K Kohansal… - Frontiers in …, 2022 - frontiersin.org
Background We aimed to determine the predictors of regression to normoglycemia and
progression to diabetes among subjects with pre-diabetes in a single model concurrently …

Predictive performance of triglyceride glucose index (TyG index) to identify glucose status conversion: a 5-year longitudinal cohort study in Chinese pre-diabetes …

X Chen, D Liu, W He, H Hu, W Wang - Journal of Translational Medicine, 2023 - Springer
Abstract Objective Triglyceride glucose index (TyG index) has been recommended as an
alternative indicator of insulin resistance. However, the association between TyG and …